Traditionally, lymphocytic interferon γ (IFN-γ) was considered to be a simple'booster'of
proinflammatory responses by microglia (brain-resident macrophages) during bacterial or …

Abstract N-methyl-d-aspartate (NMDA) receptor (NMDAR) hypofunction plays a key role in
pathophysiology of schizophrenia. Since NMDAR hypofunction has also been reported in …

This paper considers functional integration in the brain from a computational perspective.
We ask what sort of neuronal message passing is mandated by active inference—and what …

The hippocampus is crucial for episodic memory, but it is also involved in online prediction.
Evidence suggests that a unitary hippocampal code underlies both episodic memory and …

Parvalbumin inhibitory interneurons (PVIs) are crucial for maintaining proper
excitatory/inhibitory balance and high-frequency neuronal synchronization. Their activity …

Parvalbumin-expressing interneurons (PV-INs) are highly vulnerable to stressors and have
been implicated in many neuro-psychiatric diseases such as schizophrenia, Alzheimer's …

This paper revisits the dynamic causal modelling of fMRI timeseries by replacing the usual
(Taylor) approximation to neuronal dynamics with a neural mass model of the canonical …

Neuronal network dysfunction is increasingly recognized as an early symptom in
Alzheimer's disease (AD) and may provide new entry points for diagnosis and intervention …

The term spreading depolarization (SD) refers to waves of abrupt, sustained mass
depolarization in gray matter of the CNS. SD, which spreads from neuron to neuron in …

Glucose is the mandatory fuel for the brain, yet the relative contribution of glucose and
lactate for neuronal energy metabolism is unclear. We found that increased lactate, but not …