Among the intestinal pathogenic Escherichia coli, enteroinvasive E. coli (EIEC) are a group
of intracellular pathogens able to enter epithelial cells of colon, multiplicate within them, and …

The history of Shigella, the causative agent of bacillary dysentery, is a long and fascinating
one. This brief historical account starts with descriptions of the disease and its impact on …

Metastasis is facilitated by the formation of a" premetastatic niche," which is fostered by
primary tumor-derived factors. Colorectal cancer (CRC) metastasizes mainly to the liver. We …

Background Diarrhea is a serious health problem in children, with the highest mortality rate
in sub-Saharan Africa. Diarrheagenic Escherichia coli (DEC) is among the major bacterial …

Two-component signal transduction systems (TCSs) are widespread types of protein
machinery, typically consisting of a histidine kinase membrane sensor and a cytoplasmic …

Shigella spp. are one of the leading causes of infectious diarrheal diseases. They are
Escherichia coli pathovars that are characterized by the harboring of a large plasmid that …

The enteric pathogens have evolved to utilize elements from their surroundings to optimize
their infection strategies. A common mechanism to achieve this is to employ intestinal …

Some pathogenic or symbiotic Gram-negative bacteria can manipulate the ubiquitination
system of the eukaryotic host cell using a variety of strategies. Members of the genera …

Transcriptional factors play an important role in gene regulation in all organisms, especially
in Bacteria. Here special emphasis is placed in the AraC/XylS family of transcriptional …

Since the discovery of penicillin in the first half of the last century, antibiotics have become
the pillars of modern medicine for fighting bacterial infections. However, pathogens resistant …