Background Insulin resistance (IR) is one of the major hallmark for pathogenesis and
etiology of type 2 diabetes mellitus (T2DM). IR is directly interlinked with various …

The current global obesity pandemic is the leading cause for the soaring rates of metabolic
diseases, especially diabetes, cardiovascular disease, hypertension, and non-alcoholic …

MiRNAs are regulatory molecules that can be packaged into exosomes and secreted from
cells. Here, we show that adipose tissue macrophages (ATMs) in obese mice secrete …

The worldwide epidemic of obesity has brought considerable attention to research aimed at
understanding the biology of adipocytes (fat cells) and the events occurring in adipose …

Skeletal muscle contains intramyocellular lipid droplets within the cytoplasm of myocytes as
well as intermuscular adipocytes. These depots exhibit physiological and pathological …

Components of the immune system are altered in obesity and type 2 diabetes (T2D), with the
most apparent changes occurring in adipose tissue, the liver, pancreatic islets, the …

Muscle atrophy is caused by an imbalance in contractile protein synthesis and degradation
which can be triggered by various conditions including Type 2 Diabetes Mellitus (T2DM) …

Summary Omega-3 fatty acids (ω-3 FAs) have potential anti-inflammatory activity in a variety
of inflammatory human diseases, but the mechanisms remain poorly understood. Here we …

Abstract The “metabolic syndrome”(MetS) is a clustering of components that reflect
overnutrition, sedentary lifestyles, and resultant excess adiposity. The MetS includes the …

Insulin resistance (IR) plays a key role in the pathophysiology of obesity-related diseases
such as type 2 diabetes and nonalcoholic fatty liver disease. It has been demonstrated that …