Parkinson's disease (PD) is characterized by the loss of neuronal cells, which leads to
synaptic dysfunction and cognitive defects. Despite the advancements in treatment …

Highlights•Synthetic biology enables efficient phage genome engineering.•Phages with
tunable host range and antimicrobial payload delivery enhance efficacy.•Phage design …

Identifying and characterizing mobile genetic elements in sequencing data is essential for
understanding their diversity, ecology, biotechnological applications and impact on public …

Background Double-stranded DNA bacteriophages (dsDNA phages) play pivotal roles in
structuring human gut microbiomes; yet, the gut virome is far from being fully characterized …

Indigenous bacteriophage communities (virome) in the human gut have a huge impact on
the structure and function of gut bacterial communities (bacteriome), but virome variation at a …

Bacteriophages, which are viruses infecting bacteria, are the most ubiquitous and diverse
entities in the biosphere. There is accumulating evidence revealing their important roles in …

Despite the accelerating number of uncultivated virus sequences discovered in
metagenomics and their apparent importance for health and disease, the human gut virome …

The exponential growth of biomedical data in recent years has urged the application of
numerous machine learning techniques to address emerging problems in biology and …

Bacteriophages (phages) are obligate parasites that use host bacterial translation
machinery to produce viral proteins. However, some phages have alternative genetic codes …

Nowadays, bacteriophages are increasingly considered as an alternative treatment for a
variety of bacterial infections in cases where classical antibiotics have become ineffective …