Hydrogen isotopes are unique tools for identifying and understanding biological and
chemical processes. Hydrogen isotope labelling allows for the traceless and direct …

Proteins adopt different higher-order structures (HOS) to enable their unique biological
functions. Understanding the complexities of protein higher-order structures and dynamics …

Polymeric electronic materials have enabled soft and stretchable electronics. However, the
lack of a universal micro/nanofabrication method for skin-like and elastic circuits results in …

Photoaffinity labeling (PAL) using a chemical probe to covalently bind its target in response
to activation by light has become a frequently used tool in drug discovery for identifying new …

Conspectus Bioorthogonal chemistry has found increased application in living systems over
the past decade. In particular, tetrazine bioorthogonal chemistry has become a powerful tool …

Photoaffinity labeling (PAL) is a powerful technique in chemical biology and chemical
proteomics, and has been successfully demonstrated on a variety of non-covalent molecular …

Ceramides draw wide attention as tumor suppressor lipids that act directly on mitochondria
to trigger apoptotic cell death. However, molecular details of the underlying mechanism are …

Protein-protein interactions (PPIs) trigger a wide range of biological signaling pathways that
are crucial for biomedical research and drug discovery. Various techniques have been used …

The widespread applications of benzophenone (BP) photochemistry in biological chemistry,
bioorganic chemistry, and material science have been prominent in both academic and …

Indirect cell–cell interactions mediated by secreted proteins and their plasma membrane
receptors play essential roles for regulating intercellular signaling. However, systematic …