The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance

H Tegally, JE San, M Cotten, M Moir, B Tegomoh… - Science, 2022 - science.org
Investment in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing
in Africa over the past year has led to a major increase in the number of sequences that …

Distribution and current state of molecular genetic characterization in pathogenic free-living amoebae

A Otero-Ruiz, LD Gonzalez-Zuñiga… - Pathogens, 2022 - mdpi.com
Free-living amoebae (FLA) are protozoa widely distributed in the environment, found in a
great diversity of terrestrial biomes. Some genera of FLA are linked to human infections. The …

Tracking SARS-CoV-2 introductions in Mozambique using pandemic-scale phylogenies: a retrospective observational study

FJ Martínez-Martínez, AJ Massinga… - The Lancet Global …, 2023 - thelancet.com
Background From the start of the SARS-CoV-2 outbreak, global sequencing efforts have
generated an unprecedented amount of genomic data. Nonetheless, unequal sampling …

Transmission networks of SARS-CoV-2 in Coastal Kenya during the first two waves: A retrospective genomic study

CN Agoti, LI Ochola-Oyier, S Dellicour, KS Mohammed… - Elife, 2022 - elifesciences.org
Background: Detailed understanding of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) regional transmission networks within sub-Saharan Africa is key for guiding …

Multi-omics in COVID-19: Seeing the unseen but overlooked in the clinic

T Lu, Y Wang, T Guo - Cell Reports Medicine, 2022 - cell.com
COVID-19 is an ongoing pandemic of global concern and is unlikely to disappear. This
commentary discusses how multi-omics technologies have helped uncover the molecular …

Insights from Zimbabwe's SARS-CoV-2 genomic surveillance

T Dzinamarira, S Mukwenha, Z Mukandavire… - The Lancet Global …, 2021 - thelancet.com
Understanding the genomic epidemiology of SARS-CoV-2 is essential in developing
effective public health policy and control programmes. The Article by Tapfumanei Mashe …

Genomic epidemiology of SARS-CoV-2 during the first four waves in Mozambique

N Ismael, S van Wyk, H Tegally… - PLOS Global Public …, 2023 - journals.plos.org
Mozambique reported the first case of coronavirus disease 2019 (COVID-19) in March 2020
and it has since spread to all provinces in the country. To investigate the introductions and …

[HTML][HTML] COVID-19 impact on EuroTravNet infectious diseases sentinel surveillance in Europe

MP Grobusch, L Weld, JL Schnyder, CS Larsen… - Travel Medicine and …, 2023 - Elsevier
Background The COVID-19 pandemic resulted in a sharp decline of post-travel patient
encounters at the European sentinel surveillance network (EuroTravNet) of travellers' health …

Scalable neighbour search and alignment with uvaia

L de Oliveira Martins, AE Mather, AJ Page - PeerJ, 2024 - peerj.com
Despite millions of SARS-CoV-2 genomes being sequenced and shared globally,
manipulating such data sets is still challenging, especially selecting sequences for focused …

Clinical impact of plasma concentrations of first-line antituberculosis drugs

R Perumal, K Naidoo, A Naidoo… - South African Medical …, 2023 - ajol.info
Background. The clinical significance of low antituberculosis (anti-TB) drug concentrations
has not been fully elucidated. Objectives. To investigate the clinical consequences of first …