Molecular basis of astrocyte diversity and morphology across the CNS in health and disease
Astrocytes, a type of glia, are abundant and morphologically complex cells. Here, we report
astrocyte molecular profiles, diversity, and morphology across the mouse central nervous …
astrocyte molecular profiles, diversity, and morphology across the mouse central nervous …
Astrocytes in chronic pain: cellular and molecular mechanisms
HJ Lu, YJ Gao - Neuroscience Bulletin, 2023 - Springer
Chronic pain is challenging to treat due to the limited therapeutic options and adverse side-
effects of therapies. Astrocytes are the most abundant glial cells in the central nervous …
effects of therapies. Astrocytes are the most abundant glial cells in the central nervous …
Astrocytes as master modulators of neural networks: Synaptic functions and disease‐associated dysfunction of astrocytes
JA Stogsdill, CC Harwell… - Annals of the New York …, 2023 - Wiley Online Library
Astrocytes are the most abundant glial cell type in the central nervous system and are
essential to the development, plasticity, and maintenance of neural circuits. Astrocytes are …
essential to the development, plasticity, and maintenance of neural circuits. Astrocytes are …
Mode of action of astrocytes in pain: From the spinal cord to the brain
Y Chen, X Feng, CW Cheung, JA Liu - Progress in Neurobiology, 2022 - Elsevier
Chronic pain is a maladaptive condition affecting 7%− 10% of the population worldwide and
can be accompanied by depression, anxiety, and insomnia. In particular, chronic pain is …
can be accompanied by depression, anxiety, and insomnia. In particular, chronic pain is …
Multicore fiber optic imaging reveals that astrocyte calcium activity in the mouse cerebral cortex is modulated by internal motivational state
Astrocytes are a direct target of neuromodulators and can influence neuronal activity on
broad spatial and temporal scales in response to a rise in cytosolic calcium. However, our …
broad spatial and temporal scales in response to a rise in cytosolic calcium. However, our …
Sculpting astrocyte diversity through circuits and transcription
Astrocytes are the most abundant glial cell in the central nervous system and occupy a wide
range of roles that are essential for brain function. Over the past few years, evidence has …
range of roles that are essential for brain function. Over the past few years, evidence has …
[HTML][HTML] Lesion-remote astrocytes govern microglia-mediated white matter repair
S McCallum, KB Suresh, T Islam, AW Saustad… - …, 2024 - pmc.ncbi.nlm.nih.gov
Spared regions of the damaged central nervous system undergo dynamic remodeling and
exhibit a remarkable potential for therapeutic exploitation. Here, lesion-remote astrocytes …
exhibit a remarkable potential for therapeutic exploitation. Here, lesion-remote astrocytes …
Sex-specific astrocyte regulation of spinal motor circuits by Nkx6. 1
Astrocytes exhibit diverse cellular and molecular properties across the central nervous
system (CNS). Recent studies identified region-specific transcription factors (TF) that …
system (CNS). Recent studies identified region-specific transcription factors (TF) that …
A method for selective and efficient isolation of gray matter astrocytes from the spinal cord of adult mice
A growing body of evidence indicates intra-and inter-regional heterogeneity of astrocytes in
the brain. However, because of a lack of an efficient method for isolating astrocytes from the …
the brain. However, because of a lack of an efficient method for isolating astrocytes from the …
[HTML][HTML] Multicore fiber optic imaging reveals that astrocyte calcium activity in the cerebral cortex is modulated by internal motivational state
Astrocytes are a direct target of neuromodulators and can influence neuronal activity on
broad spatial and temporal scales through their close proximity to synapses. However, our …
broad spatial and temporal scales through their close proximity to synapses. However, our …