Unlocking the magic in mycelium: Using synthetic biology to optimize filamentous fungi for biomanufacturing and sustainability

C Jo, J Zhang, JM Tam, GM Church, AS Khalil… - Materials Today Bio, 2023 - Elsevier
Filamentous fungi drive carbon and nutrient cycling across our global ecosystems, through
its interactions with growing and decaying flora and their constituent microbiomes. The …

[HTML][HTML] Automation and artificial intelligence in filamentous fungi-based bioprocesses: A review

S Wainaina, MJ Taherzadeh - Bioresource Technology, 2023 - Elsevier
By utilizing their powerful metabolic versatility, filamentous fungi can be utilized in
bioprocesses aimed at achieving circular economy. With the current digital transformation …

Recent advances in the development of Aspergillus for protein production

Q Li, J Lu, G Zhang, S Liu, J Zhou, G Du, J Chen - Bioresource Technology, 2022 - Elsevier
Aspergillus had been widely used in the industrial production of recombinant proteins. In
addition to the safety and broad substrate utilization spectrum, its efficient post-translational …

[HTML][HTML] Fungal cell factories for efficient and sustainable production of proteins and peptides

M Lübeck, PS Lübeck - Microorganisms, 2022 - mdpi.com
Filamentous fungi are a large and diverse taxonomically group of microorganisms found in
all habitats worldwide. They grow as a network of cells called hyphae. Since filamentous …

The phenomenon of strain degeneration in biotechnologically relevant fungi

C Danner, RL Mach, AR Mach-Aigner - Applied Microbiology and …, 2023 - Springer
Fungi are widely exploited for large-scale production in the biotechnological industry to
produce a diverse range of substances due to their versatility and relative ease of growing …

Cephalosporin C biosynthesis and fermentation in Acremonium chrysogenum

L Liu, Z Chen, W Liu, X Ke, X Tian, J Chu - Applied Microbiology and …, 2022 - Springer
Cephalosporins are currently the most widely used antibiotics in clinical practice. The main
strain used for the industrial production cephalosporin C (CPC) is Acremonium …

Engineering of non-model eukaryotes for bioenergy and biochemical production

D Ploessl, Y Zhao, Z Shao - Current Opinion in Biotechnology, 2023 - Elsevier
Highlights•Scenario evaluation and in silico tools streamline host selection and
construction.•Advances in filamentous fungi have expanded the scope of non-model host …

Gradient porous structures of mycelium: a quantitative structure–mechanical property analysis

E Olivero, E Gawronska, P Manimuda, D Jivani… - Scientific Reports, 2023 - nature.com
Gradient porous structures (GPS) are characterized by structural variations along a specific
direction, leading to enhanced mechanical and functional properties compared to …

Comprehensively dissecting the hub regulation of PkaC on high‐productivity and pellet macromorphology in citric acid producing Aspergillus niger

X Zheng, TC Cairns, X Ni, L Zhang, H Zhai… - Microbial …, 2022 - Wiley Online Library
Aspergillus niger, an important industrial workhorse for citric acid production, is
characterized by polar hyphal growth with complex pelleted, clumped or dispersed …

Fungal‐Based Biorefinery: From Renewable Resources to Organic Acids

L Varriale, R Ulber - ChemBioEng Reviews, 2023 - Wiley Online Library
Biorefineries are facilities in which lignocellulosic biomasses are converted in a wide range
of bioproducts facilitating the transition from the use of petrochemical resources to …