Influenza A viruses (IAVs) are contagious pathogens responsible for severe respiratory
infection in humans and animals worldwide. Upon detection of IAV infection, host immune …

Background A previous aggregate data meta-analysis of randomised controlled trials
showed that vitamin D supplementation reduces the rate of asthma exacerbations requiring …

Respiratory syncytial virus (RSV) is amongst the most important pathogenic infections of
childhood and is associated with significant morbidity and mortality. Although there have …

Current data indicate that the “bronchiolitis” diagnosis comprises more than one condition.
Clinically, pathophysiologically, and even genetically three main clusters of patients can be …

The interleukin (IL)-17 family includes six structure-related cytokines (A–F). To date, majority
of studies have focused on IL-17A. IL-17A plays a pivotal role in various infectious diseases …

Respiratory Syncytial Virus (RSV) is the commonest cause of severe respiratory infection in
infants, leading to over 3 million hospitalizations and around 66,000 deaths worldwide each …

Viral infections cause substantial human morbidity and mortality, and are a significant health
burden worldwide. Following a viral infection, the host may initiate complex antiviral immune …

Evidence has increasingly shown that the lungs are a major site of immune regulation. A
robust and highly regulated immune response in the lung protects the host from pathogen …

A first step in primary disease prevention is identifying common, modifiable risk factors that
contribute to a significant proportion of disease development. Infant respiratory viral infection …

Human respiratory syncytial virus (hRSV) is a major cause of respiratory disease and
hospitalisation of infants, worldwide, and is also responsible for significant morbidity in …