Consensus guidelines and recommendations for infection prevention in multiple myeloma: a report from the International Myeloma Working Group

NS Raje, E Anaissie, SK Kumar, S Lonial… - The Lancet …, 2022 - thelancet.com
Infection remains the leading cause of morbidity and mortality in patients with multiple
myeloma because of the cumulative effect of disease, treatment, and host-related factors …

Recommendations for vaccination in multiple myeloma: a consensus of the European Myeloma Network

H Ludwig, M Boccadoro, P Moreau, J San-Miguel… - Leukemia, 2021 - nature.com
Vaccination is one of the most successful medical interventions that has saved the life of
millions of people. Vaccination is particularly important in patients with multiple myeloma …

[HTML][HTML] Multiple myeloma and infections: a population-based study on 9253 multiple myeloma patients

C Blimark, E Holmberg, UH Mellqvist, O Landgren… - …, 2015 - ncbi.nlm.nih.gov
Infections are a major cause of morbidity and mortality in patients with multiple myeloma. To
estimate the risk of bacterial and viral infections in multiple myeloma patients, we used …

COVID-19 vaccination in patients with multiple myeloma: a consensus of the European Myeloma Network

H Ludwig, P Sonneveld, T Facon… - The Lancet …, 2021 - thelancet.com
Patients with multiple myeloma frequently present with substantial immune impairment and
an increased risk for infections and infection-related mortality. The risk for infection with …

Monoclonal gammopathy of undetermined significance

TH Mouhieddine, LD Weeks… - Blood, The Journal of …, 2019 - ashpublications.org
Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant plasma
cell dyscrasia that consistently precedes multiple myeloma (MM) with a 1% risk of …

Epidemiology, genetics and treatment of multiple myeloma and precursor diseases

K Hemminki, A Försti, R Houlston… - International journal of …, 2021 - Wiley Online Library
Multiple myeloma (MM) is a hematological malignancy caused by the clonal expansion of
plasma cells. The incidence of MM worldwide is increasing with greater than 140 000 …

Prevention of infections including vaccination strategies in multiple myeloma

H Ludwig, S Kumar - American journal of hematology, 2023 - Wiley Online Library
Infections are a major cause of morbidity and mortality in multiple myeloma. The increased
risk for bacterial and viral infections results mainly from the disease‐inherent and treatment …

Inflammation and infection in plasma cell disorders: how pathogens shape the fate of patients

J Caro, M Braunstein, L Williams, B Bruno… - Leukemia, 2022 - nature.com
The role of infection and chronic inflammation in plasma cell disorders (PCD) has been well-
described. Despite not being a diagnostic criterion, infection is a common complication of …

High-density neutrophils in MGUS and multiple myeloma are dysfunctional and immune-suppressive due to increased STAT3 downstream signaling

A Romano, NL Parrinello, V Simeon, F Puglisi… - Scientific reports, 2020 - nature.com
To understand neutrophil impairment in the progression from MGUS through active MM, we
investigated the function of mature, high-density neutrophils (HDNs), isolated from …

Secondary immunodeficiency in lymphoproliferative malignancies

V Friman, O Winqvist, C Blimark… - Hematological …, 2016 - Wiley Online Library
Secondary immunodeficiencies occur as a consequence of various diseases, including
hematological malignancies, and the use of pharmacological therapies, such as …