Plants as biofactories for therapeutic proteins and antiviral compounds to combat COVID-19

C England, J TrejoMartinez, P PerezSanchez, U Karki… - Life, 2023 - mdpi.com
The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) had a profound impact on the world's health and …

Integrating genome-wide CRISPR screens and in silico drug profiling for targeted antidote development

B Wang, Y Xu, AH Wan, G Wan, QP Wang - Nature Protocols, 2024 - nature.com
Numerous toxins threaten humans, but specific antidotes are unavailable for most of them.
Although CRISPR screening has aided the discovery of the mechanisms of some toxins …

GC–MS analysis, molecular docking, and apoptotic-based cytotoxic effect of Caladium lindenii Madison extracts toward the HeLa cervical cancer cell line

A Kalsoom, A Altaf, M Sarwar, T Maqbool… - Scientific Reports, 2024 - nature.com
Utilizing medicinal plants and other natural resources to prevent different types of human
cancers is the prime focus of attention. Cervical cancer in women ranks as the fourth most …

Gene expression and anticancer evaluation of Kigelia africana (Lam.) Benth. Extracts using MDA-MB-231 and MCF-7 cell lines

A Kalsoom, A Altaf, H Sattar, T Maqbool, M Sajjad… - Plos one, 2024 - journals.plos.org
In recent years, a cancer research trend has shifted towards identifying novel therapeutic
compounds from natural assets for the management of cancer. In this study, we aimed to …

The Potential Role of Medicinal Plants, Traditional Herbal Medicines, and Formulations to Overcome SARS-CoV-2 Induced Health Crisis

M Halder, R Bose, S Jha - Medicinal Plants: Biodiversity, Biotechnology …, 2023 - Springer
Since December 2019, the infection of Severe Acute Respiratory Syndrome-related
Coronavirus 2 (SARS-CoV-2), also known as novel coronavirus, has been responsible for …

[PDF][PDF] Identification of FDA compounds to inhibit RAGEs through docking, MD-simulation, MMPBSA and DFT analysis

AP Singh, S Ahmad, K Raza, HK Gautam - 2023 - assets-eu.researchsquare.com
Receptor for advanced glycation end products (RAGEs) is a multifunctional cell surface
protein present in vascular cells, monocytes/macrophages, B-and T-lymphocytes, retina …