Soluble sugars serve five main purposes in multicellular organisms: as sources of carbon
skeletons, osmolytes, signals, and transient energy storage and as transport molecules …

Iron is an indispensable metabolic cofactor in both pro-and eukaryotes, which engenders a
natural competition for the metal between bacterial pathogens and their human or animal …

The Orientations of Proteins in Membranes (OPM) database provides a collection of
transmembrane, monotopic and peripheral proteins from the Protein Data Bank whose …

Membrane transport proteins that transduce free energy stored in electrochemical ion
gradients into a concentration gradient are a major class of membrane proteins. We report …

▪ Abstract The cell membrane Na, K-ATPase is a member of the P-type family of active cation
transport proteins. Recently the molecular structure of the related sarcoplasmic reticulum Ca …

The severe acute respiratory syndrome associated coronavirus 2 (SARS-CoV-2) and SARS-
CoV-1 accessory protein Orf3a colocalizes with markers of the plasma membrane, endocytic …

Site-directed spin labeling is a general method for investigating structure and conformational
switching in soluble and membrane proteins. It will also be an important tool for exploring …

Revised and updated, Chemical Reagents for Protein Modification, Third Edition is an
encyclopedic work describing the many approaches to the site-specific modification of …

An X-ray structure of the lactose permease of Escherichia coli (LacY) in an inward-facing
conformation has been solved. LacY contains N-and C-terminal domains, each with six …

Although many polar residues are directly involved in transmembrane protein functions, the
extent to which they contribute to more general structural features is still unclear. Previous …