Bacterial genomes encode the biosynthetic potential to produce hundreds of thousands of
complex molecules with diverse applications, from medicine to agriculture and materials …

As synthetic biology permeates society, the signal processing circuits in engineered living
systems must be customized to meet practical demands. Towards this mission, novel …

The shape of a plant's root system influences its ability to reach essential nutrients in the soil
and to acquire water during drought. Progress in engineering plant roots to optimize water …

Synthetic biology is the discipline of engineering application-driven biological functionalities
that were not evolved by nature. Early breakthroughs of cell engineering, which were based …

Whole-cell biocatalysts have proven a tractable path toward sustainable production of bulk
and fine chemicals. Yet the screening of libraries of cellular designs to identify best …

Living organisms have evolved a plethora of sensing systems for the intra-and extracellular
detection of small molecules, ions or physical parameters. Several recent studies have …

Plants and microbes communicate to collaborate to stop pests, scavenge nutrients, and
react to environmental change. Microbiota consisting of thousands of species interact with …

Synthetic biology has the potential to bring forth advanced genetic devices for applications
in healthcare and biotechnology. However, accurately predicting the behavior of engineered …

The rise of systems biology has ushered a new paradigm: the view of the cell as a system
that processes environmental inputs to drive phenotypic outputs. Synthetic biology provides …

Regulated transgene expression is an integral component of gene therapies, cell therapies
and biomanufacturing. However, transcription factor-based regulation, upon which most …