Quantitative phase imaging techniques for the study of cell pathophysiology: from principles to applications
A cellular-level study of the pathophysiology is crucial for understanding the mechanisms
behind human diseases. Recent advances in quantitative phase imaging (QPI) techniques …
behind human diseases. Recent advances in quantitative phase imaging (QPI) techniques …
Spatial light interference microscopy: principle and applications to biomedicine
In this paper, we review spatial light interference microscopy (SLIM), a common-path, phase-
shifting interferometer, built onto a phase-contrast microscope, with white-light illumination …
shifting interferometer, built onto a phase-contrast microscope, with white-light illumination …
Quantitative phase imaging (QPI) in neuroscience
Quantitative phase imaging (QPI) is an emerging label-free modality that attracts significant
interest in biomedicine in general and neuroscience in particular. Based on the principle of …
interest in biomedicine in general and neuroscience in particular. Based on the principle of …
Prediction of prostate cancer recurrence using quantitative phase imaging
S Sridharan, V Macias, K Tangella, A Kajdacsy-Balla… - Scientific reports, 2015 - nature.com
The risk of biochemical recurrence of prostate cancer among individuals who undergo
radical prostatectomy for treatment is around 25%. Current clinical methods often fail at …
radical prostatectomy for treatment is around 25%. Current clinical methods often fail at …
Real time blood testing using quantitative phase imaging
We demonstrate a real-time blood testing system that can provide remote diagnosis with
minimal human intervention in economically challenged areas. Our instrument combines …
minimal human intervention in economically challenged areas. Our instrument combines …
Optofluidic time-stretch imaging–an emerging tool for high-throughput imaging flow cytometry
Optical imaging is arguably the most effective tool to visualize living cells with high
spatiotemporal resolution and in a nearly noninvasive manner. Driven by this capability …
spatiotemporal resolution and in a nearly noninvasive manner. Driven by this capability …
Imaging a full set of optical scattering properties of biological tissue by inverse spectroscopic optical coherence tomography
We here develop a method to measure and image the full optical scattering properties by
inverse spectroscopic optical coherence tomography (ISOCT). Tissue is modelled as a …
inverse spectroscopic optical coherence tomography (ISOCT). Tissue is modelled as a …
Solving inverse scattering problems in biological samples by quantitative phase imaging
Quantitative phase imaging (QPI), a method that precisely recovers the wavefront of an
electromagnetic field scattered by a transparent, weakly scattering object, is a rapidly …
electromagnetic field scattered by a transparent, weakly scattering object, is a rapidly …
Label-free optical quantification of structural alterations in Alzheimer's disease
We present a wide-field quantitative label-free imaging of mouse brain tissue slices with sub-
micrometre resolution, employing holographic microscopy and an automated scanning …
micrometre resolution, employing holographic microscopy and an automated scanning …
Interferometric time-stretch microscopy for ultrafast quantitative cellular and tissue imaging at 1 μm
Quantitative phase imaging (QPI) has been proven to be a powerful tool for label-free
characterization of biological specimens. However, the imaging speed, largely limited by the …
characterization of biological specimens. However, the imaging speed, largely limited by the …