Background Insecticide‐treated nets (ITNs) and indoor residual spraying (IRS) are used to
prevent malaria transmission. Both interventions use insecticides to kill mosquitoes that bite …

The scale-up of malaria control efforts has led to marked reductions in malaria burden over
the past twenty years, but progress has slowed. Implementation of indoor residual spraying …

Five years of sustained indoor residual spraying (IRS) of insecticide from 2014 to 2019, first
using a carbamate followed by an organophosphate, was associated with a marked …

Pirimiphos-methyl is a pro-insecticide requiring activation by mosquito cytochrome P450
enzymes to induce toxicity while PBO blocks activation of these enzymes in pyrethroid …

High-malaria burden countries in sub-Saharan Africa are shifting from malaria control
towards elimination. Hence, there is need to gain a contemporary understanding of how …

Background Malaria is a major cause of morbidity and mortality globally, especially in sub-
Saharan Africa. Widespread resistance to pyrethroids threatens the gains achieved by …

The diversity of Plasmodium falciparum within human hosts requires parasite population
size be defined in terms of parasite variation rather than the number of infected hosts. To …

Abstract Background The Global Fund alone contributed 56% of all international financing
for malaria and has invested more than US $13.5 billion in malaria treatment, prevention …

Progress in malaria control has stalled in recent years. With growing resistance to existing
malaria vector control insecticides and the introduction of new vector control products …

Supporting malaria control with interfaced applications of mathematical models that enables
investigating effectiveness of various interventions as well as their cost implications could be …