Systemic pharmacological treatments for chronic plaque psoriasis: a network meta‐analysis

E Sbidian, A Chaimani, R Guelimi… - Cochrane Database …, 2023 - cochranelibrary.com
Background Psoriasis is an immune‐mediated disease with either skin or joints
manifestations, or both, and it has a major impact on quality of life. Although there is …

Assessing the relative efficacy of interleukin-17 and interleukin-23 targeted treatments for moderate-to-severe plaque psoriasis: a systematic review and network meta …

LM Sawyer, K Malottki, C Sabry-Grant, N Yasmeen… - PloS one, 2019 - journals.plos.org
Introduction New generation biologics, including interleukin (IL)-17 and IL-23 inhibitors,
have delivered higher rates of skin clearance than older treatments in head-to-head studies …

PD-1 up-regulation on CD4+ T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-β1 production

LJ Celada, JA Kropski, JD Herazo-Maya… - Science translational …, 2018 - science.org
Pulmonary fibrosis is a progressive inflammatory disease with high mortality and limited
therapeutic options. Previous genetic and immunologic investigations suggest common …

A systematic review and meta-analysis of the efficacy and safety of the interleukin (IL)-12/23 and IL-17 inhibitors ustekinumab, secukinumab, ixekizumab, brodalumab …

J Bilal, A Berlinberg, S Bhattacharjee… - Journal of …, 2018 - Taylor & Francis
Objective: To systematically analyze the efficacy and safety of interleukin (IL)-12/23, IL-17,
and selective IL-23 inhibitors in moderate to severe plaque psoriasis. Methods and results …

Human αβ and γδ T cells in skin immunity and disease

MS Cruz, A Diamond, A Russell… - Frontiers in …, 2018 - frontiersin.org
γδ T lymphocytes maintain skin homeostasis by balancing keratinocyte differentiation and
proliferation with the destruction of infected or malignant cells. An imbalance in skin-resident …

[HTML][HTML] Quantitative evaluation of biologic therapy options for psoriasis: a systematic review and network meta-analysis

ZK Jabbar-Lopez, ZZN Yiu, V Ward, LS Exton… - Journal of Investigative …, 2017 - Elsevier
Multiple biologic treatments are licensed for psoriasis. The lack of head-to-head randomized
controlled trials makes choosing between them difficult for patients, clinicians, and guideline …

Comparing the efficacy and tolerability of biologic therapies in psoriasis: an updated network meta‐analysis

SK Mahil, MC Ezejimofor, LS Exton… - British Journal of …, 2020 - academic.oup.com
Background The rapid expansion of psoriasis biologics has led to an urgent need to
understand their relative efficacy and tolerability to inform treatment decisions better and …

“Inflammatory skin march” in atopic dermatitis and psoriasis

M Furue, T Kadono - Inflammation Research, 2017 - Springer
Background Comorbidities of cardiovascular diseases (CVDs), metabolic syndrome and
autoimmune diseases with systemic inflammation are recent topics in medicine …

Psoriasis and atopic dermatitis

CEM Griffiths, P van de Kerkhof… - Dermatology and …, 2017 - Springer
Psoriasis and atopic dermatitis are common, chronic inflammatory skin diseases. We
discuss several aspects of these disorders, including: risk factors; incidence and prevalence; …

Long-term safety of nine systemic medications for psoriasis: A cohort study using the Spanish Registry of Adverse Events for Biological Therapy in Dermatological …

E Daudén, G Carretero, R Rivera, C Ferrándiz… - Journal of the American …, 2020 - Elsevier
Background Registry studies broadly describing the safety of systemic drugs in psoriasis are
needed. Objective To describe the safety findings of the systemic drugs acitretin …