Diagnosis by microbial culture, breath tests and urinary excretion tests, and treatments of small intestinal bacterial overgrowth

Y Maeda, T Murakami - Antibiotics, 2023 - mdpi.com
Small intestinal bacterial overgrowth (SIBO) is characterized as the increase in the number
and/or alteration in the type of bacteria in the upper gastrointestinal tract and accompanies …

[HTML][HTML] Interplay between Bile Acids and Intestinal Microbiota: Regulatory Mechanisms and Therapeutic Potential for Infections

W Li, H Chen, J Tang - Pathogens, 2024 - mdpi.com
Bile acids (BAs) play a crucial role in the human body's defense against infections caused
by bacteria, fungi, and viruses. BAs counteract infections not only through interactions with …

Intestinal bile acids provide a surmountable barrier against C. difficile TcdB-induced disease pathogenesis

S Icho, JS Ward, J Tam, LK Kociolek… - Proceedings of the …, 2023 - National Acad Sciences
Intestinal bile acids play an essential role in the Clostridioides difficile lifecycle having been
shown in vitro to modulate various aspects of pathogenesis, including spore germination …

The microbial-derived bile acid lithocholate and its epimers inhibit Clostridioides difficile growth and pathogenicity while sparing members of the gut microbiota

SC Kisthardt, R Thanissery, CM Pike… - Journal of …, 2023 - Am Soc Microbiol
Clostridioides difficile is a Gram-positive, spore-forming anaerobe that causes clinical
diseases ranging from diarrhea and pseudomembranous colitis to toxic megacolon and …

Deoxycholic acid inducing chronic atrophic gastritis with colonic mucosal lesion correlated to mucosal immune dysfunction in rats

Y Cheng, S Wang, W Zhu, Z Xu, L Xiao, J Wu… - Scientific Reports, 2024 - nature.com
The present study aimed to explore the underlying mechanism of bile reflux-inducing
chronic atrophic gastritis (CAG) with colonic mucosal lesion. The rat model of CAG with …

[HTML][HTML] Assessing causal associations of bile acids with obesity indicators: A Mendelian randomization study

C Huang, S Xu, R Chen, Y Ding, Q Fu, B He, T Jiang… - Medicine, 2024 - journals.lww.com
Maintaining a balanced bile acids (BAs) metabolism is essential for lipid and cholesterol
metabolism, as well as fat intake and absorption. The development of obesity may be …

Integrated multi‐omics analysis reveals unique signatures of paclitaxel‐loaded poly(lactide‐co‐glycolide) nanoparticles treatment of head and neck cancer cells

M Haider, J Jagal, K Bajbouj, BM Sharaf… - …, 2023 - Wiley Online Library
The use of poly (lactide‐co‐glycolide)(PLGA) nanoparticles (NPs) as carriers for
chemotherapeutic drugs is regarded as an actively targeted nano‐therapy for the specific …

[PDF][PDF] Interplay between Bile Acids and Intestinal Microbiota: Regulatory Mechanisms and Strategic Interventions for Infections

W Li, H Chen, J Tang - 2024 - preprints.org
Bile acids (BAs) play a crucial role in the human body's defense against infections caused
by bacteria, fungi, and viruses. BAs counteract infections not only through interactions with …

Mechanisms of Clostridioides difficile Environmental Sensing: from Bile Acids to Pseudoproteases

E Forster - 2023 - search.proquest.com
Clostridioides difficile is an anaerobic, spore-forming bacterium that is a leading cause of
nosocomial infections in the United States. Its aerotolerant spores are the transmissible …

[PDF][PDF] Quelle est la place de la transplantation de matériel fécal dans la prise en charge des infections à Clostridium difficile face aux autres traitements

V VERMERSCH - researchportal.unamur.be
Cliniques universitaires Saint-Luc, service de gastro-entérologie pédiatrique, février 2014.
Un petit patient âgé de six ans seulement est admis pour une infection à Clostridium difficile …