Mapping the consequences of impaired synaptic plasticity in schizophrenia through development: an integrative model for diverse clinical features
JK Forsyth, DA Lewis - Trends in cognitive sciences, 2017 - cell.com
Schizophrenia is associated with alterations in sensory, motor, and cognitive functions that
emerge before psychosis onset; identifying pathogenic processes that can account for this …
emerge before psychosis onset; identifying pathogenic processes that can account for this …
Gray matter alterations in schizophrenia high-risk youth and early-onset schizophrenia: a review of structural MRI findings
BK Brent, HW Thermenos… - Child and …, 2013 - childpsych.theclinics.com
Neuroimaging studies over the last 4 decades have provided overwhelming evidence that
schizophrenia is a disorder involving widespread abnormalities of brain structure. 1 It is …
schizophrenia is a disorder involving widespread abnormalities of brain structure. 1 It is …
A review of neuroimaging studies of young relatives of individuals with schizophrenia: a developmental perspective from schizotaxia to schizophrenia
HW Thermenos, MS Keshavan… - American Journal of …, 2013 - Wiley Online Library
In an effort to identify the developing abnormalities preceding psychosis, Dr. Ming T. Tsuang
and colleagues at Harvard expanded Meehl's concept of “schizotaxia,” and examined brain …
and colleagues at Harvard expanded Meehl's concept of “schizotaxia,” and examined brain …
Sleep dysfunction prior to the onset of schizophrenia: A review and neurodevelopmental diathesis–stress conceptualization.
JR Lunsford-Avery, VA Mittal - Clinical Psychology: Science and …, 2013 - psycnet.apa.org
Sleep dysfunction is a pervasive symptom in schizophrenia, yet little is known regarding the
extent to which problematic sleep is present prior to illness onset. Results from an online …
extent to which problematic sleep is present prior to illness onset. Results from an online …
Clinical, cognitive, and neuroimaging evidence of a neurodevelopmental continuum in offspring of probands with schizophrenia and bipolar disorder
G Sugranyes, E de la Serna, R Borras… - Schizophrenia …, 2017 - academic.oup.com
Background Studies in child and adolescent offspring of patients with schizophrenia or
bipolar disorders may help understand the influence of neurodevelopmental factors on the …
bipolar disorders may help understand the influence of neurodevelopmental factors on the …
Daily stressors and negative life events in children at elevated risk of developing schizophrenia
BackgroundPsychological stress is implicated in the development of schizophrenia, but little
is known about experiences of stress among children at elevated risk for the disorder …
is known about experiences of stress among children at elevated risk for the disorder …
Hippocampus and amygdala volumes in children and young adults at high-risk of schizophrenia: research synthesis
R Ganzola, M Maziade, S Duchesne - Schizophrenia Research, 2014 - Elsevier
Background Studies have reported hippocampal and amygdala volume abnormalities in
schizophrenic patients. It is necessary to explore the potential for these structures as early …
schizophrenic patients. It is necessary to explore the potential for these structures as early …
Brain structure, IQ, and psychopathology in young offspring of patients with schizophrenia or bipolar disorder
Background. Studying offspring of schizophrenia (SZo) and bipolar disorder patients (BDo)
provides important information on the putative neurodevelopmental trajectories underlying …
provides important information on the putative neurodevelopmental trajectories underlying …
Hippocampal volume development in healthy siblings of childhood-onset schizophrenia patients
A Mattai, A Hosanagar, B Weisinger… - American Journal of …, 2011 - Am Psychiatric Assoc
Objective: Previous anatomic studies have established a reduction in hippocampal volume
in schizophrenia, but few have investigated the progressive course of these changes and …
in schizophrenia, but few have investigated the progressive course of these changes and …
Comparative study on the functional connectivity of amygdala and hippocampal neural circuits in patients with first-episode schizophrenia and other high-risk …
X Wang, Z Yin, Q Sun, X Jiang, L Chao, X Dai… - Frontiers in …, 2021 - frontiersin.org
Objective: Cortical-limbic system neural circuit abnormalities are closely related to the onset
of schizophrenia (SZ). The amygdala, hippocampus, cingulate, and prefrontal lobe are …
of schizophrenia (SZ). The amygdala, hippocampus, cingulate, and prefrontal lobe are …