Breast cancer risk associated with germline likely pathogenic/pathogenic variants (PV)
varies by gene, often by penetrance (high> 50% or moderate 20–50%), and specific locus …

Ovarian cancer is a complex disease, mostly observed in postmenopausal women, and is
associated with poor survival rates. It is the sixth most common cancer and the fifth most …

BACKGROUND Increasing numbers of BReast CAncer (BRCA) 1 or 2 pathogenic variant
(PV) carriers, who have an inherited predisposition to breast and ovarian cancer, are being …

Globally, ovarian cancer is the eighth most common cancer in women, accounting for an
estimated 3.7% of cases and 4.7% of cancer deaths in 2020. Until the early 2000s, age …

Millions of women have given preference to the use of combined oral contraceptives (COCs)
since its introduction in the 1960s. Both oestrogens and progestogens can regulate …

Endometriosis is a chronic, universal, and prevalent disease estimated to affect up to 1: 10
women of reproductive age. Endometriosis-associated ovarian cancer (EAOC) developing …

It remains inconclusive whether the use of oral contraceptives (OCs) alters the risks of breast
or ovarian cancer in women with a breast cancer susceptibility gene 1 (BRCA1) or breast …

Ovarian cancer is the seventh most common cancer in women in the world, with an
estimated worldwide mortality of over 207′ 000 women every year. This cancer, due to the …

Ovarian cancer is a leading cause of death among women with gynecological cancers, and
is often diagnosed at advanced stages, leading to poor outcomes. This review explores …

Abstract Background BRCA1 and BRCA2 (BRCA) mutation carriers face a high lifetime risk
of developing ovarian cancer. Oral contraceptives are protective in this population; however …