State of the evidence 2017: an update on the connection between breast cancer and the environment
JM Gray, S Rasanayagam, C Engel, J Rizzo - Environmental Health, 2017 - Springer
Background In this review, we examine the continually expanding and increasingly
compelling data linking radiation and various chemicals in our environment to the current …
compelling data linking radiation and various chemicals in our environment to the current …
Familial/inherited cancer syndrome: a focus on the highly consanguineous Arab population
FS AlHarthi, A Qari, A Edress… - NPJ genomic medicine, 2020 - nature.com
The study of hereditary cancer, which accounts for~ 10% of cancer cases worldwide is an
important subfield of oncology. Our understanding of hereditary cancers has greatly …
important subfield of oncology. Our understanding of hereditary cancers has greatly …
[HTML][HTML] The association between BRCA1 gene polymorphism and cancer risk: a meta-analysis
GP Xu, Q Zhao, D Wang, WY Xie, LJ Zhang, H Zhou… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Many studies have reported that BRCA1 polymorphisms are associated with cancer risk, but
the results remain controversial. The purpose of this meta-analysis is to evaluate the …
the results remain controversial. The purpose of this meta-analysis is to evaluate the …
Performance of single-nucleotide polymorphisms in breast cancer risk prediction models: a systematic review and meta-analysis
Background: SNP risk information can potentially improve the accuracy of breast cancer risk
prediction. We aim to review and assess the performance of SNP-enhanced risk prediction …
prediction. We aim to review and assess the performance of SNP-enhanced risk prediction …
Exome sequencing in a family with luminal-type breast cancer underpinned by variation in the methylation pathway
N Van der Merwe, AV Peeters, FM Pienaar… - International journal of …, 2017 - mdpi.com
Panel-based next generation sequencing (NGS) is currently preferred over whole exome
sequencing (WES) for diagnosis of familial breast cancer, due to interpretation challenges …
sequencing (WES) for diagnosis of familial breast cancer, due to interpretation challenges …
Polymorphism of DNA repair genes via homologous recombination (HR) in ovarian cancer
B Smolarz, MM Michalska, D Samulak… - Pathology & Oncology …, 2019 - Springer
Ovarian cancer is one of the most common types of cancer in women. The repair system via
homologous recombination repairs double-strand breaks (DSB) of DNA, which are the most …
homologous recombination repairs double-strand breaks (DSB) of DNA, which are the most …
Targeted sequencing to discover germline variants in the BRCA1 and BRCA2 genes in a Russian population and their association with breast cancer risk
SA Solodskikh, AV Panevina, MV Gryaznova… - Mutation Research …, 2019 - Elsevier
BRCA1 and BRCA2 are tumor suppressor genes involved in the repair of DNA damage and
transcriptional regulation of the cell cycle. Alterations in BRCA1/2 lead to production of …
transcriptional regulation of the cell cycle. Alterations in BRCA1/2 lead to production of …
Common variation in BRCA1 may have a role in progression to lethal prostate cancer after radiation treatment
BACKGROUND: To evaluate whether single-nucleotide polymorphisms (SNPs) reflecting
common variation in the tumor suppressor BRCA1 affect prostate cancer outcomes …
common variation in the tumor suppressor BRCA1 affect prostate cancer outcomes …
[PDF][PDF] Meta-analysis of BRCA1 polymorphisms and breast cancer susceptibility
S Ghafouri-Fard, A Dianatpour, S Faramarzi - Klin Onkol, 2018 - linkos.cz
Background: BRCA1 codes for a tumor suppressor protein involved in DNA repair. Based on
the role of single nucleotide polymorphisms (SNPs) in the modification of gene expression …
the role of single nucleotide polymorphisms (SNPs) in the modification of gene expression …
Mutations in BRCA-related breast and ovarian cancer in the South African Indian population: a descriptive study
Abstract Knowledge of the genetic landscape of a specific population group is vital for
population-specific diagnosis and treatment of familial breast cancer. Although BRCA …
population-specific diagnosis and treatment of familial breast cancer. Although BRCA …