Wound healing is a complex, dynamic process supported by a myriad of cellular events that
must be tightly coordinated to efficiently repair damaged tissue. Derangement in wound …

Acute myocardial infarction is caused by a sudden coronary artery occlusion and leads to
ischemia in the corresponding myocardial territory which generally results in myocardial …

Macrophages play a central role in the development of atherosclerotic cardiovascular
disease (ASCVD), which encompasses coronary artery disease, peripheral artery disease …

Amino acid metabolism is a critical regulator of the immune response, and its modulating
becomes a promising approach in various forms of immunotherapy. Insufficient …

Macrophages respond to microbial ligands and various noxious cues by initiating an
inflammatory response aimed at eliminating the original pathogenic insult. Transition of …

Macrophages are innate immune cells that adopt diverse activation states in response to
their microenvironment. Editing macrophage activation to dampen inflammatory diseases by …

After activation, cells of the myeloid lineage undergo robust metabolic transitions, as well as
discrete epigenetic changes, that can dictate both ongoing and future inflammatory …

The arginase enzyme developed in early life forms and was maintained during evolution. As
the last step in the urea cycle, arginase cleaves l-arginine to form urea and l-ornithine. The …

Inflammatory processes are firmly established as central to the development and
complications of cardiovascular diseases. Elevated levels of inflammatory markers have …

Neuroinflammation has positive and negative effects. This review focuses on the roles of
macrophage in the PNS. Transection of PNS axons leads to degeneration and clearance of …