Plants including Rhizoma polgonati, Smilax china, and Trigonella foenum-graecum contain
a lot of diosgenin, a steroidal sapogenin. This bioactive phytochemical has shown high …

Diosgenin (DG), a well‐known steroidal sapogenin, is present abundantly in medicinal
herbs such as Dioscorea rhizome, Dioscorea villosa, Trigonella foenum-graecum, Smilax …

Alzheimer's disease (AD) is a chronic neurodegenerative brain disorder characterized by
memory impairment, dementia, and oxidative stress in elderly people. Currently, only a few …

The theory of aging is primarily concerned with oxidative stress caused by an imbalance in
reactive oxygen species generation and cellular antioxidants. To alleviate the oxidative …

Diosgenin is a neurosteroid derived from the plants and has been previously reported for its
numerous health beneficial properties, such as anti-arrhythmic, hypolipidemic, and …

The purpose of this study was to evaluate the effects of diosgenin on the D-galactose-
induced cerebral cortical widely dispersed apoptosis. Male 12-week-old Wistar rats were …

Backgroud Use of multifunctional drugs with neurotrophic supporting and oxidative stress
suppressing activity may be considered a therapeutic strategy to protect or repair cellular …

Multiple sclerosis (MS) is a chronic autoimmune demyelinating disease of the central
nervous system. Currently, there is no drug available to cure this kind of disease. Diosgenin …

Background: An annual plant, Fenugreek (Trigonellafoenum-graecum L.) has well-known
health care benefits in Ayurvedic and Chinese medicine. Its leaves and seeds have …

Preclinical studies have shown that diosgenin, a steroidal sapogenin, is a promising
phytochemical for treating different pathological conditions, such as cancer, diabetes, and …