Substance use disorders occur commonly in patients with schizophrenia and dramatically
worsen their overall clinical course. While the exact mechanisms contributing to substance …

Cannabis use has become increasingly accepted socially and legally, for both recreational
and medicinal purposes. Without reliable information about the effects of cannabis, people …

Exposure to intermittent repeated social defeat (IRSD) increases the vulnerability of mice to
the rewarding effects of cocaine in the conditioned place preference (CPP) paradigm …

Background: Cocaine dependence is an important problem without any effective
pharmacological treatment. Some preclinical studies have suggested that cannabidiol …

Purpose Despite our considerable experience with the problem of addiction in our specialty,
most anesthesia care providers don't know how to identify or help an impaired colleague …

Cannabis use is typically initiated during adolescence and is a significant risk factor for the
development of cocaine use in adulthood. However, no preclinical studies have examined …

The relationship between stress and drug use is well demonstrated. Stress-induced by
repeated social defeat (RSD) enhances the conditioned place preference (CPP) induced by …

The mechanism behind the reinstament of psychostimulant, as a major obstacle in addiction
treatment is not fully understood. Controversial data are available in the literature …

Synthetic cannabinoids have exhibited unpredictable abuse liabilities, especially self-
administration (SA) responses in normal rodent models, despite seemingly inducing …

Chronic cannabinoid consumption is an increasingly common behavior among teenagers
and has been shown to cause long-lasting neurobehavioral alterations. Besides, it has been …