Scar management in burn injuries using drug delivery and molecular signaling: current treatments and future directions

S Amini-Nik, Y Yousuf, MG Jeschke - Advanced drug delivery reviews, 2018 - Elsevier
In recent decades, there have been tremendous improvements in burn care that have
allowed patients to survive severe burn injuries that were once fatal. However, a major …

[HTML][HTML] Techniques for colorectal anastomosis

YH Ho, MAT Ashour - World Journal of Gastroenterology: WJG, 2010 - ncbi.nlm.nih.gov
Colorectal anastomotic leak remains one of the most feared post-operative complications,
particularly after anterior resection of the rectum with, the shift from abdomino-peritoneal …

[HTML][HTML] Fracture mechanics of collagen fibrils: influence of natural cross-links

RB Svensson, H Mulder, V Kovanen, SP Magnusson - Biophysical journal, 2013 - cell.com
Tendons are important load-bearing structures, which are frequently injured in both sports
and work. Type I collagen fibrils are the primary components of tendons and carry most of …

[HTML][HTML] Effects of maturation and advanced glycation on tensile mechanics of collagen fibrils from rat tail and Achilles tendons

RB Svensson, ST Smith, PJ Moyer, SP Magnusson - Acta biomaterialia, 2018 - Elsevier
Connective tissues are ubiquitous throughout the body and consequently affect the function
of many organs. In load bearing connective tissues like tendon, the mechanical functionality …

Matrix metalloproteinase inhibitor GM 6001 attenuates keratinocyte migration, contraction and myofibroblast formation in skin wounds

U Mirastschijski, CJ Haaksma, JJ Tomasek… - Experimental cell …, 2004 - Elsevier
In this study, we examined the impact of matrix metalloproteinases (MMP) on
epithelialization, granulation tissue development, wound contraction, and α-smooth muscle …

Metalloproteinases and their inhibitors—diagnostic and therapeutic opportunities in orthopedics

B Pasternak, P Aspenberg - Acta orthopaedica, 2009 - Taylor & Francis
Matrix metalloproteinases (MMPs) and related enzymes (ADAMs, ADAMTS) and their
inhibitors control matrix turnover and function. Recent advances in our understanding of …

[PDF][PDF] Peritoneal molecular environment, adhesion formation and clinical implication

N Chegini - Front Biosci, 2002 - article.imrpress.com
Clinical implication 3. Molecular events in peritoneal adhesion formation 3.1. Inflammatory
mediators and adhesion formation 3.2. The role chemokines and cytokines 4. Angiogenesis …

[HTML][HTML] Matrix metalloproteinases: how much can they do?

MS Ågren, U auf dem Keller - International journal of molecular sciences, 2020 - mdpi.com
Zinc-dependent matrix metalloproteinases (MMPs) belong to metzincins that comprise not
only 23 human MMPs but also other metalloproteinases, such as 21 human ADAMs (a …

A multicentre cohort study of serum and peritoneal biomarkers to predict anastomotic leakage after rectal cancer resection

CL Sparreboom, N Komen, D Rizopoulos… - Colorectal …, 2020 - Wiley Online Library
Aim Anastomotic leakage (AL) is one of the most feared complications after rectal resection.
This study aimed to assess a combination of biomarkers for early detection of AL after rectal …

Collagenase-1 (MMP-1), matrilysin-1 (MMP-7), and stromelysin-2 (MMP-10) are expressed by migrating enterocytes during intestinal wound healing

MT Salmela, SLF Pender… - Scandinavian journal …, 2004 - Taylor & Francis
Background: Matrix metalloproteinases (MMPs) play a crucial role in wound healing of the
skin, airways, and cornea, but data on MMPs in normal intestinal wound healing is limited …