The plastic brain: neurotoxicity of micro-and nanoplastics

M Prüst, J Meijer, RHS Westerink - Particle and fibre toxicology, 2020 - Springer
Given the global abundance and environmental persistence, exposure of humans and
(aquatic) animals to micro-and nanoplastics is unavoidable. Current evidence indicates that …

Reactive oxygen species: Physiological and physiopathological effects on synaptic plasticity: Supplementary issue: Brain plasticity and repair

TF Beckhauser, J Francis-Oliveira… - Journal of …, 2016 - journals.sagepub.com
In the mammalian central nervous system, reactive oxygen species (ROS) generation is
counterbalanced by antioxidant defenses. When large amounts of ROS accumulate …

Distribution, elimination, and toxicity of silver nanoparticles and silver ions in rats after 28-day oral exposure

M Van der Zande, RJ Vandebriel, E Van Doren… - ACS …, 2012 - ACS Publications
We report the results of a 28-day oral exposure study in rats, exposed to< 20 nm noncoated,
or< 15 nm PVP-coated silver nanoparticles ([Ag]= 90 mg/kg body weight (bw)), or AgNO3 …

Effect of sub-dermal exposure of silver nanoparticles on hepatic, renal and cardiac functions accompanying oxidative damage in male Wistar rats

JO Olugbodi, B Lawal, G Bako, AS Onikanni… - Scientific Reports, 2023 - nature.com
Silver nanoparticles (AgNPs) have been generally used due to their strong antibacterial,
antiviral and antifungal and antimicrobial properties. However, their toxicity is a subject of …

[HTML][HTML] Developmental impacts and toxicological hallmarks of silver nanoparticles across diverse biological models

Y Wāng, Y Han, DX Xu - Environmental Science and Ecotechnology, 2024 - Elsevier
Silver nanoparticles (AgNPs), revered for their antimicrobial prowess, have become
ubiquitous in a range of products, from biomedical equipment to food packaging. However …

Silver nanoparticles induce protective autophagy via Ca2+/CaMKKβ/AMPK/mTOR pathway in SH-SY5Y cells and rat brains

L Li, L Li, X Zhou, Y Yu, Z Li, D Zuo, Y Wu - Nanotoxicology, 2019 - Taylor & Francis
Silver nanoparticles (AgNPs) are widely used for manufacturing products containing
antibacterial agents, as well as food technologies such as edible films and food packaging …

[HTML][HTML] Neurotoxicity of nanoscale materials

A Karmakar, Q Zhang, Y Zhang - Journal of Food and Drug Analysis, 2014 - Elsevier
Nanotechnology has been applied in consumer products and commercial applications,
showing a significant impact on almost all industries and all areas of society. Significant …

A systematic review of evidence for silver nanoparticle-induced mitochondrial toxicity

LL Maurer, JN Meyer - Environmental Science: Nano, 2016 - pubs.rsc.org
Silver nanoparticles (AgNPs) are extensively used for their antibacterial properties in a
diverse set of applications, ranging from the treatment of municipal wastewater to infection …

Gut dysbiosis and neurobehavioral alterations in rats exposed to silver nanoparticles

AB Javurek, D Suresh, WG Spollen, ML Hart… - Scientific reports, 2017 - nature.com
Due to their antimicrobial properties, silver nanoparticles (AgNPs) are being used in non-
edible and edible consumer products. It is not clear though if exposure to these chemicals …

Silver nanoparticles induce tight junction disruption and astrocyte neurotoxicity in a rat blood–brain barrier primary triple coculture model

L Xu, M Dan, A Shao, X Cheng, C Zhang… - International journal …, 2015 - Taylor & Francis
Background Silver nanoparticles (Ag-NPs) can enter the brain and induce neurotoxicity.
However, the toxicity of Ag-NPs on the blood–brain barrier (BBB) and the underlying …