Recent advances on high-efficiency of microRNAs in different types of lung cancer: a comprehensive review

MS Sadeghi, M Lotfi, N Soltani, E Farmani… - Cancer Cell …, 2023 - Springer
Carcinoma of the lung is among the most common types of cancer globally. Concerning its
histology, it is categorized as a non-small cell carcinoma (NSCLC) and a small cell cancer …

MicroRNA-34 family in cancers: role, mechanism, and therapeutic potential

J Fu, S Imani, MY Wu, RC Wu - Cancers, 2023 - mdpi.com
Simple Summary The dysregulation of the miR-34 family has been shown to play an
important role in tumorigenesis and cancer progression. In this review, we summarized the …

Exploring the therapeutic significance of microRNAs and lncRNAs in kidney diseases

LA Bravo-Vázquez, S Paul, MG Colín-Jurado… - Genes, 2024 - mdpi.com
MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are two crucial classes of
transcripts that belong to the major group of non-coding RNAs (ncRNAs). These RNA …

Regulation and therapeutic potentials of microRNAs to non-small cell lung cancer

MT Le, HT Nguyen, XH Nguyen, XH Do, BT Mai… - Heliyon, 2023 - cell.com
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for
80%–85% of total cases and leading to millions of deaths worldwide. Drug resistance is the …

Exosomal fragment enclosed polyamine-salt nano-complex for co-delivery of docetaxel and mir-34a exhibits higher cytotoxicity and apoptosis in breast cancer cells

M Basak, M Kulkarni, S Narisepalli, D Chitkara… - Scientific Reports, 2024 - nature.com
A novel core–shell nanocarrier system has been designed for co-delivery of a small
anticancer drug, docetaxel (DTX) and tumor suppressor (TS) miR-34a named as Exo …

Revolutionizing cancer therapy: nanoformulation of miRNA-34–enhancing delivery and efficacy for various cancer immunotherapies: a review

MP Fawzy, HAFM Hassan, NK Sedky, MS Nafie… - Nanoscale …, 2024 - pubs.rsc.org
Despite recent advancements in cancer therapies, challenges such as severe toxic effects,
non-selective targeting, resistance to chemotherapy and radiotherapy, and recurrence of …

Delivery of miRNAs Using Nanoparticles for the Treatment of Osteosarcoma

C Wang, Y Zhang, W Kong, X Rong… - International Journal …, 2024 - Taylor & Francis
Osteosarcoma is the predominant primary malignant bone tumor that poses a significant
global health challenge. MicroRNAs (miRNAs) that regulate gene expression are associated …

Sex differences in cancer and immunotherapy outcomes: the role of androgen receptor

J Zhao, Q Wang, AF Tan, CJL Loh, HC Toh - Frontiers in Immunology, 2024 - frontiersin.org
Across the wide range of clinical conditions, there exists a sex imbalance where biological
females are more prone to autoimmune diseases and males to some cancers. These …

MicroRNAs and proteolytic cleavage of receptors in cancers: A comprehensive review of regulatory interactions and therapeutic implications

F Hosseinpour-Soleimani, Z Salmasi, Y Ghasemi… - Heliyon, 2024 - cell.com
Cancer remains a challenging disease worldwide, necessitating innovative approaches to
better comprehend its underlying molecular mechanisms and devise effective therapeutic …

Unlocking novel therapeutic avenues in glioblastoma: Harnessing 4-amino cyanine and miRNA synergy for next-gen treatment convergence

K Sandhanam, T Tamilanban, K Manasa… - Neuroscience, 2024 - Elsevier
Glioblastoma (GBM) poses a formidable challenge in oncology due to its aggressive nature
and dismal prognosis, with average survival rates around 15 months despite conventional …