Myelodysplastic syndromes: 2023 update on diagnosis, risk‐stratification, and management

G Garcia‐Manero - American journal of hematology, 2023 - Wiley Online Library
Disease overview The myelodysplastic syndromes (MDS) are a very heterogeneous group
of myeloid disorders characterized by peripheral blood cytopenias and increased risk of …

Current challenges and unmet medical needs in myelodysplastic syndromes

U Platzbecker, AS Kubasch, C Homer-Bouthiette… - Leukemia, 2021 - nature.com
Myelodysplastic syndromes (MDS) represent a heterogeneous group of myeloid neoplasms
that are characterized by ineffective hematopoiesis, variable cytopenias, and a risk of …

Clinical effect of point mutations in myelodysplastic syndromes

R Bejar, K Stevenson, O Abdel-Wahab… - … England Journal of …, 2011 - Mass Medical Soc
Background Myelodysplastic syndromes are clinically heterogeneous disorders
characterized by clonal hematopoiesis, impaired differentiation, peripheral-blood …

Myelodysplastic syndromes: 2018 update on diagnosis, risk‐stratification and management

G Montalban‐Bravo… - American journal of …, 2018 - Wiley Online Library
Disease overview The myelodysplastic syndromes (MDS) are a very heterogeneous group
of myeloid disorders characterized by peripheral blood cytopenias and increased risk of …

Myelodysplastic syndromes

A Tefferi, JW Vardiman - New England Journal of Medicine, 2009 - Mass Medical Soc
This review gives an account of the clinical and hematologic features of the myelodysplastic
syndromes. It supplies the latest classification of these disorders, discusses the cytogenetic …

Validation of a prognostic model and the impact of mutations in patients with lower-risk myelodysplastic syndromes

R Bejar, KE Stevenson, BA Caughey… - Journal of clinical …, 2012 - ascopubs.org
Purpose A subset of patients with myelodysplastic syndromes (MDS) who are predicted to
have lower-risk disease as defined by the International Prognostic Scoring System (IPSS) …

Myelodysplastic syndromes

L Adès, R Itzykson, P Fenaux - The Lancet, 2014 - thelancet.com
Myelodysplastic syndromes are clonal marrow stem-cell disorders, characterised by
ineffective haemopoiesis leading to blood cytopenias, and by progression to acute myeloid …

Myelodysplastic syndromes: contemporary review and how we treat

N Gangat, MM Patnaik, A Tefferi - American journal of …, 2016 - Wiley Online Library
Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal stem cell disorders
with an inherent tendency for leukemic transformation. Diagnosis is currently based on the …

Randomized phase 2 study of low-dose decitabine vs low-dose azacitidine in lower-risk MDS and MDS/MPN

E Jabbour, NJ Short, G Montalban-Bravo… - Blood, The Journal …, 2017 - ashpublications.org
Hypomethylating agents (HMAs) improve survival in patients with higher-risk
myelodysplastic syndromes (MDS) but are less well-studied in lower-risk disease. We …

Recent developments in myelodysplastic syndromes

R Bejar, DP Steensma - Blood, The Journal of the American …, 2014 - ashpublications.org
Once thought to be rare disorders, the myelodysplastic syndromes (MDS) are now
recognized as among the most common hematological neoplasms, probably affecting> 30 …