Booster COVID-19 vaccines for immune-mediated inflammatory disease patients: a systematic review and meta-analysis of efficacy and safety

ARYB Lee, SY Wong, SH Tay - Vaccines, 2022 - mdpi.com
Background: Seroconversion and longevity of vaccine-induced immune response is blunted
in immune-mediated inflammatory disease (IMID) patients owing to immunosuppressive …

[HTML][HTML] Efficacy and safety of mRNA and AstraZeneca COVID-19 vaccines in patients with autoimmune rheumatic diseases: A systematic review

AI Joudeh, AQ Lutf, S Mahdi, G Tran - Vaccine, 2023 - Elsevier
Background Patients with autoimmune rheumatic diseases (ARD) are at a potentially higher
risk for COVID-19 infection complications. Given their inherent altered immune system and …

Breakthrough SARS–CoV‐2 Infections in Patients With Immune‐Mediated Disease Undergoing B Cell–Depleting Therapy: A Retrospective Cohort Analysis

CM Calabrese, E Kirchner, EM Husni… - Arthritis & …, 2022 - Wiley Online Library
Objective Patients with immune‐mediated inflammatory diseases (IMIDs) receiving B cell–
depleting therapy (BCDT) are among the most vulnerable to severe COVID‐19, as well as …

Immunogenicity and safety of a fourth COVID-19 vaccination in rituximab-treated patients: an open-label extension study

D Mrak, E Simader, D Sieghart, P Mandl… - Annals of the …, 2022 - ard.bmj.com
Objectives Patients under rituximab therapy are at high risk for a severe COVID-19 disease
course. Humoral immune responses to SARS-CoV-2 vaccination are vastly diminished in B …

The four ws of the fourth dose COVID-19 vaccines: Why, who, when and what

KW Khong, R Zhang, IFN Hung - Vaccines, 2022 - mdpi.com
With the emergence of SARS-CoV-2 variants, vaccine breakthrough is a major public health
concern. With evidence of reduced neutralizing antibody activity against Omicron variants …

Microfluidic antibody profiling after repeated SARS-CoV-2 vaccination links antibody affinity and concentration to impaired immunity and variant escape in patients on …

A Priddey, MXH Chen-Xu, DJ Cooper… - Frontiers in …, 2024 - frontiersin.org
Background Patients with autoimmune/inflammatory conditions on anti-CD20 therapies,
such as rituximab, have suboptimal humoral responses to vaccination and are vulnerable to …

Overview of infections as an etiologic factor and complication in patients with vasculitides

P Theofilis, A Vordoni, M Koukoulaki… - Rheumatology …, 2022 - Springer
Vasculitides, a form of inflammatory autoimmune disease targeting the vessels, constitute an
entity with significant morbidity and mortality. Infections have long been associated with …

B cell reconstitution is associated with COVID-19 booster vaccine responsiveness in patients previously seronegative treated with rituximab

K Schultz, D Jannat-Khah, R Spiera - The Journal of rheumatology, 2023 - jrheum.org
Objective To assess factors associated with serologic response to the coronavirus 2019
(COVID-19) booster vaccine in patients with autoimmune rheumatic diseases treated with …

Managing Immunosuppression in Vasculitis Patients in Times of Coronavirus Disease 2019

SE Sattui, ZS Wallace - Rheumatic Disease Clinics, 2023 - rheumatic.theclinics.com
The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has represented a major challenge to …

BA. 1/BA. 5 Immunogenicity, Reactogenicity, and Disease Activity after COVID-19 Vaccination in Patients with ANCA-Associated Vasculitis: A Prospective …

C Speer, M Töllner, L Benning, M Bartenschlager… - Viruses, 2023 - mdpi.com
Emerging omicron subtypes with immune escape lead to inadequate vaccine response with
breakthrough infections in immunocompromised individuals such as Anti-neutrophil …