Intracellular VHHs to monitor and modulate GPCR signaling

P Raynaud, C Gauthier, V Jugnarain… - Frontiers in …, 2022 - frontiersin.org
Single-domain antibody fragments, also known as VHHs or nanobodies, have opened
promising avenues in therapeutics and in exploration of intracellular processes. Because of …

Harnessing Neuron Type-Specific GPCR Targets and Tools for Precision Analgesia

DF Lee - 2024 - search.proquest.com
Opioid analgesics are broadly used to manage severe pain, however they are responsible
for harmful side effects, like addiction, hyperalgesia, constipation, and lethal opioid-induced …