The proliferation marker thymidine kinase 1 in clinical use

J Zhou, E He, S Skog - Molecular and clinical oncology, 2013 - spandidos-publications.com
Tumor-related biomarkers are used for the diagnosis, prognosis and monitoring of
treatments and follow-up of cancer patients, although only a few are fully accepted for the …

Serological thymidine kinase 1 is a biomarker for early detection of tumours—a health screening study on 35,365 people, using a sensitive chemiluminescent dot blot …

ZH Chen, SQ Huang, Y Wang, AZ Yang, J Wen, XH Xu… - Sensors, 2011 - mdpi.com
Serological thymidine kinase 1 (STK1) is a reliable proliferation marker for prognosis,
monitoring tumour therapy, and relapse. Here we investigated the use of STK1 in health …

Posttranslational modifications pattern in clear cell renal cell carcinoma

CD Ene, MN Penescu, SR Georgescu, M Tampa… - Metabolites, 2020 - mdpi.com
Posttranslational modifications are dynamic enzymatic-mediated processes, regulated in
time and space, associated with cancer development. We aimed to evaluate the significance …

Ultrasound‐Accelerated, Concise, and Highly Efficient Synthesis of 2‐Oxazoline Derivatives Using Heterogenous Calcium Ferrite Nanoparticles and Their DFT …

A Bendi, S Atri, GBD Rao, MJ Raza… - Journal of …, 2021 - Wiley Online Library
A rapid and operationally simple approach for synthesising biologically relevant 2‐oxazoline
derivatives has been developed through highly efficient ultrasound‐promoted coupling …

Circulating tumor M2 pyruvate kinase and thymidine kinase 1 are potential predictors for disease recurrence in renal cell carcinoma after nephrectomy

B Nisman, V Yutkin, H Nechushtan, ON Gofrit, T Peretz… - Urology, 2010 - Elsevier
OBJECTIVES: Pyruvate kinase type M2 (TuM2-PK) and thymidine kinase 1 (TK1) are the key
enzymes involved in tumor cells metabolism and proliferation. We explored the association …

Elevated serum thymidine kinase activity in canine splenic hemangiosarcoma*

DH Thamm, DA Kamstock, CR Sharp… - Veterinary and …, 2012 - Wiley Online Library
Thymidine kinase 1 (TK1) is a soluble biomarker associated with DNA synthesis. This
prospective study evaluated serum TK1 activity in dogs presenting with hemoabdomen and …

[HTML][HTML] Methods for the evaluation of biomarkers in patients with kidney and liver diseases: multicentre research programme including ELUCIDATE RCT

PJ Selby, RE Banks, W Gregory… - … Grants for Applied …, 2018 - journalslibrary.nihr.ac.uk
Background Protein biomarkers with associations with the activity and outcomes of diseases
are being identified by modern proteomic technologies. They may be simple, accessible …

Elevated serum thymidine kinase 1 predicts risk of pre/early cancerous progression

S Huang, J Lin, N Guo, M Zhang, X Yun… - Asian Pac J Cancer …, 2011 - journal.waocp.org
Background: Serological thymidine kinase 1 (STK1) is a reliable proliferation marker for
prognosis, monitoring tumour therapy, relapse and detection of malignancies. In this study …

[PDF][PDF] 一种新肿瘤生长相关生物标志物胸苷激酶1 临床应用进展

刘秀菊, 周际, 李远, 刘森波, 方聪… - 中国药理学与毒理学 …, 2011 - cjpt.magtechjournal.com
胸苷激酶1 (TK1) 是一种嘧啶补救途径的激酶, 能催化脱氧胸苷磷酸化为一腺胸苷酸,
与细胞周期调控和细胞增殖密切相关. 多项实验证明, TK1 可用于健康体检, 肿瘤早期筛查 …

Serum thymidine kinase 1 activity in solid tumor (breast and colorectal cancer) patients treated with adjuvant chemotherapy

M Bolayirli, C Papila, GG Korkmaz… - Journal of clinical …, 2013 - Wiley Online Library
Background The aim of this study was to evaluate the changing of TK 1 (where TK is
thymidine kinase) activity before and after adjuvant chemotherapy in patients with breast …