Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …

One hundred years ago, Ramón y Cajal, considered by many as the founder of modern
neuroscience, stated that neurons of the adult central nervous system (CNS) are incapable …

Axon regeneration can be induced across anatomically complete spinal cord injury (SCI),
but robust functional restoration has been elusive. Whether restoring neurological functions …

Injured neurons in the adult mammalian central nervous system often die and seldom
regenerate axons. To uncover transcriptional pathways that could ameliorate these …

Axons differ in their growth potential: whereas during development, axons rapidly grow to
their targets, in the adult mammalian, CNS axons have lost their ability to grow and therefore …

Spinal cord injury (SCI) often leads to physical limitations, persistent pain, and major lifestyle
shifts, enhancing the likelihood of prolonged psychological stress and associated disorders …

Breakthroughs with rapid changes are the themes of the development in Neurorestoratology
this year. Given the very difficult circumstances of the persistent COVID-19 pandemic, most …

Introduction Spinal cord injury (SCI) affects 25,000–50,000 people around the world each
year and there is no cure for SCI patients currently. The primary injury damages spinal cord …

Oxidative stress is a key factor leading to profound neurological deficits following spinal cord
injury (SCI). In this study, we present the development and potential application of an iridium …

Axon growth enables the rapid wiring of the central nervous system. Understanding this
process is a prerequisite to retriggering it under pathological conditions, such as a spinal …