Recent trends in metabolic engineering of microbial chemical factories
Y Liu, J Nielsen - Current opinion in biotechnology, 2019 - Elsevier
Highlights•Microbial cell factories can be tailored for producing certain 'drop-in'chemicals.•
Metabolic engineering has greatly enhanced the development of microbial cell …
Metabolic engineering has greatly enhanced the development of microbial cell …
Can the world's favorite fruit, tomato, provide an effective biosynthetic chassis for high-value metabolites?
Tomato has a relatively short growth cycle (fruit ready to pick within 65–85 days from
planting) and a relatively high yield (the average for globe tomatoes is 3–9 kg fruit per plant …
planting) and a relatively high yield (the average for globe tomatoes is 3–9 kg fruit per plant …
Transcriptional control of photosynthetic capacity: conservation and divergence from Arabidopsis to rice
Photosynthesis is one of the most important biological processes on Earth. It provides the
consumable energy upon which almost all organisms are dependent, and modulates the …
consumable energy upon which almost all organisms are dependent, and modulates the …
[HTML][HTML] Diatom isoprenoids: Advances and biotechnological potential
A Athanasakoglou, SC Kampranis - Biotechnology advances, 2019 - Elsevier
Diatoms are among the most productive and ecologically important groups of microalgae in
contemporary oceans. Due to their distinctive metabolic and physiological features, they …
contemporary oceans. Due to their distinctive metabolic and physiological features, they …
Defining optimal electron transfer partners for light-driven cytochrome P450 reactions
SB Mellor, MH Vinde, AZ Nielsen, GT Hanke… - Metabolic …, 2019 - Elsevier
Plants and cyanobacteria are promising heterologous hosts for metabolic engineering, and
particularly suited for expression of cytochrome P450 (P450s), enzymes that catalyse key …
particularly suited for expression of cytochrome P450 (P450s), enzymes that catalyse key …
Plant diterpenoid metabolism for manufacturing the biopharmaceuticals of tomorrow: prospects and challenges
Plant diterpenoids encompass a diverse group of more than ten thousand specialized
(traditionally termed 'secondary') metabolites with significant ecological functions and …
(traditionally termed 'secondary') metabolites with significant ecological functions and …
Energetic considerations for engineering novel biochemistries in photosynthetic organisms
Humans have been harnessing biology to make valuable compounds for generations. From
beer and biofuels to pharmaceuticals, biology provides an efficient alternative to industrial …
beer and biofuels to pharmaceuticals, biology provides an efficient alternative to industrial …
Prospects of chloroplast metabolic engineering for developing nutrient-dense food crops
Addressing nutritional deficiencies in food crops through biofortification is a sustainable
approach to tackling malnutrition. Biofortification is continuously being attempted through …
approach to tackling malnutrition. Biofortification is continuously being attempted through …
Upstream biomanufacturing of pharmaceutical colchicine
G Sivakumar - Critical reviews in biotechnology, 2018 - Taylor & Francis
The plant-based colchicine potentially affects major diseases such as cardiovascular events,
cancers and gout. Gloriosa superba seeds are a conventional pharmaceutical source of …
cancers and gout. Gloriosa superba seeds are a conventional pharmaceutical source of …
IntEResting structures: formation and applications of organized smooth endoplasmic reticulum in plant cells
The endoplasmic reticulum (ER) is an organelle with remarkable plasticity, capable of
rapidly changing its structure to accommodate different functions based on intra-and …
rapidly changing its structure to accommodate different functions based on intra-and …