Raman spectroscopy in cell biology and microbiology

G Pezzotti - Journal of Raman Spectroscopy, 2021 - Wiley Online Library
The Raman spectrum of living cells and microorganisms contains highly specific fingerprint‐
like signatures, useful in unequivocally identifying different species and interpreting …

Emerging antiviral strategies to interfere with influenza virus entry

E Vanderlinden, L Naesens - Medicinal research reviews, 2014 - Wiley Online Library
Influenza A and B viruses are highly contagious respiratory pathogens with a considerable
medical and socioeconomical burden and known pandemic potential. Current influenza …

Stepwise Priming by Acidic pH and a High K+ Concentration Is Required for Efficient Uncoating of Influenza A Virus Cores after Penetration

S Stauffer, Y Feng, F Nebioglu, R Heilig… - Journal of …, 2014 - Am Soc Microbiol
Influenza A virus (IAV) uses the low pH in late endocytic vacuoles as a cue for penetration by
membrane fusion. Here, we analyzed the prefusion reactions that prepare the core for …

Influenza A matrix protein M1 multimerizes upon binding to lipid membranes

M Hilsch, B Goldenbogen, C Sieben, CT Höfer… - Biophysical journal, 2014 - cell.com
The matrix protein M1 plays a pivotal role in the budding of influenza virus from the plasma
membrane (PM) of infected cells. This protein interacts with viral genetic material and …

Ubiquitin in influenza virus entry and innate immunity

A Rudnicka, Y Yamauchi - Viruses, 2016 - mdpi.com
Viruses are obligatory cellular parasites. Their mission is to enter a host cell, to transfer the
viral genome, and to replicate progeny whilst diverting cellular immunity. The role of …

At low pH, influenza virus matrix protein M1 undergoes a conformational change prior to dissociating from the membrane

J Fontana, AC Steven - Journal of virology, 2013 - Am Soc Microbiol
The M1 matrix protein of influenza A virus, which plays multiple roles in virion assembly and
infection, underlies the viral envelope. However, previous studies have given differing …

Structural analysis of influenza A virus matrix protein M1 and its self-assemblies at low pH

EV Shtykova, LA Baratova, NV Fedorova… - PloS one, 2013 - journals.plos.org
Influenza A virus matrix protein M1 is one of the most important and abundant proteins in the
virus particles broadly involved in essential processes of the viral life cycle. The absence of …

Influenza A virus uncoating

Y Yamauchi - Advances in virus research, 2020 - Elsevier
Influenza A virus (IAV) is an enveloped virus of the Orthomyxoviridae with a negative-sense
single-stranded RNA genome. During virus cell entry, viral and cellular cues are delivered in …

[HTML][HTML] Treatment of influenza virus with beta-propiolactone alters viral membrane fusion

P Bonnafous, MC Nicolaï, JC Taveau… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Beta-propiolactone (BPL) is commonly used as an inactivating reagent to produce viral
vaccines. Although BPL has been described to chemically modify nucleic acids, its effect on …

[HTML][HTML] A quantitative model for virus uncoating predicts influenza A infectivity

A Artcibasova, L Wang, S Anchisi, Y Yamauchi… - Cell reports, 2023 - cell.com
For virus infection of new host cells, the disassembly of the protective outer protein shell
(capsid) is a critical step, but the mechanisms and host-virus interactions underlying the …