The recognition that asthma is primarily an inflammatory disorder of the airways associated
with T helper type 2 (TH2) cell-dependent promotion of IgE production and recruitment of …

Asthma is a serious health and socioeconomic issue all over the world, affecting more than
300 million individuals. The disease is considered as an inflammatory disease in the airway …

Background Allergic asthma is a chronic disease of the conducting airways characterized by
TH 2 inflammation and tissue remodeling after exposure to inhaled allergens. Although the …

The initiation, magnitude and duration of an immune response against antigens are a tightly
regulated process involving a dynamic, orchestrated balance of pro-and anti-inflammatory …

Accumulating data support that vitamin D possesses several biological and molecular
actions apart from its role in calcium homeostasis. Immune cells express vitamin D receptor …

AMP-activated protein kinase (AMPK), a cellular energy sensor, has been reported to
participate in modulating inflammatory responses, but its role in intestinal inflammation …

Inflammation is the mechanism of diseases caused by microbial, autoimmune, allergic,
metabolic and physical insults that produce distinct types of inflammatory responses. This …

Natural Killer (NK) cells are cytotoxic effector lymphocytes with the ability to lyse target cells
in a major histocompatibility complex (MHC) class I-independent manner and without the …

Background Mitochondrial metabolism is known to be important for T-cell activation.
However, its involvement in effector T-cell differentiation has just begun to gain attention …

Background The release of various inflammatory mediators into the bronchial lumen is
thought to reflect both the type and degree of airway inflammation, eosinophilic Th2, and …