[HTML][HTML] The 2022 World Health Organization classification of tumours of the urinary system and male genital organs—part A: renal, penile, and testicular tumours
The fifth edition of the World Health Organization (WHO) classification of urogenital tumours
(WHO “Blue Book”), published in 2022, contains significant revisions. This review …
(WHO “Blue Book”), published in 2022, contains significant revisions. This review …
[HTML][HTML] New developments in existing WHO entities and evolving molecular concepts: The Genitourinary Pathology Society (GUPS) update on renal neoplasia
K Trpkov, O Hes, SR Williamson, AJ Adeniran… - Modern Pathology, 2021 - Elsevier
Abstract The Genitourinary Pathology Society (GUPS) reviewed recent advances in renal
neoplasia, particularly post-2016 World Health Organization (WHO) classification, to provide …
neoplasia, particularly post-2016 World Health Organization (WHO) classification, to provide …
French AFU Cancer Committee Guidelines-update 2022-2024: management of kidney cancer
P Bigot, P Barthelemy, R Boissier, ZE Khene… - Progrès en Urologie, 2022 - Elsevier
Aim To update the recommendations for the management of kidney cancers. Methods A
systematic review of the literature was conducted from 2015 to 2022. The most relevant …
systematic review of the literature was conducted from 2015 to 2022. The most relevant …
Report from the international society of urological pathology (ISUP) consultation conference on molecular pathology of urogenital cancers: III: molecular pathology of …
Renal cell carcinoma (RCC) subtypes are increasingly being discerned via their molecular
underpinnings. Frequently this can be correlated to histologic and immunohistochemical …
underpinnings. Frequently this can be correlated to histologic and immunohistochemical …
Comprehensive molecular characterization identifies distinct genomic and immune hallmarks of renal medullary carcinoma
Renal medullary carcinoma (RMC) is a highly lethal malignancy that mainly afflicts young
individuals of African descent and is resistant to all targeted agents used to treat other renal …
individuals of African descent and is resistant to all targeted agents used to treat other renal …
NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition
Disruption of antagonism between SWI/SNF chromatin remodelers and polycomb repressor
complexes drives the formation of numerous cancer types. Recently, an inhibitor of the …
complexes drives the formation of numerous cancer types. Recently, an inhibitor of the …
Association of high-intensity exercise with renal medullary carcinoma in individuals with sickle cell trait: clinical observations and experimental animal studies
DD Shapiro, M Soeung, L Perelli, E Dondossola… - Cancers, 2021 - mdpi.com
Simple Summary Renal medullary carcinoma (RMC) is a rare but highly aggressive
malignancy that affects individuals of African descent with sickle cell trait (SCT). The driver of …
malignancy that affects individuals of African descent with sickle cell trait (SCT). The driver of …
Immunohistochemistry for the diagnosis of renal epithelial neoplasms
M Akgul, SR Williamson - Seminars in Diagnostic Pathology, 2022 - Elsevier
Despite the increasing number of newly identified renal neoplasms, the diagnosis of renal
cell carcinoma (RCC) can usually be reached with careful histologic examination and a …
cell carcinoma (RCC) can usually be reached with careful histologic examination and a …
Efficacy and safety of gemcitabine plus doxorubicin in patients with renal medullary carcinoma
NR Wilson, AJ Wiele, DS Surasi, P Rao, K Sircar… - Clinical Genitourinary …, 2021 - Elsevier
Introduction Renal medullary carcinoma (RMC) is a rare and lethal renal cell carcinoma
characterized by the loss of tumor suppressor SMARCB1. Molecular profiling studies have …
characterized by the loss of tumor suppressor SMARCB1. Molecular profiling studies have …
Molecular genetics of renal cell tumors: A practical diagnostic approach
R Alaghehbandan, D Perez Montiel, AS Luis, O Hes - Cancers, 2019 - mdpi.com
Renal epithelial cell tumors are composed of a heterogeneous group of tumors with variable
morphologic, immunohistochemical, and molecular features. A “histo-molecular” approach is …
morphologic, immunohistochemical, and molecular features. A “histo-molecular” approach is …