Spatial multi-omics analyses of the tumor immune microenvironment

WC Hsieh, BR Budiarto, YF Wang, CY Lin… - Journal of Biomedical …, 2022 - Springer
In the past decade, single-cell technologies have revealed the heterogeneity of the tumor-
immune microenvironment at the genomic, transcriptomic, and proteomic levels and have …

Advances in structure elucidation of small molecules using mass spectrometry

T Kind, O Fiehn - Bioanalytical reviews, 2010 - Springer
The structural elucidation of small molecules using mass spectrometry plays an important
role in modern life sciences and bioanalytical approaches. This review covers different soft …

What can we learn from ambient ionization techniques?

H Chen, G Gamez, R Zenobi - Journal of the American Society for …, 2011 - ACS Publications
Ambient mass spectrometry—mass spectrometric analysis with no or minimal effort for
sample preparation—has experienced a very rapid development during the last 5 years …

Desorption sonic spray ionization for (high) voltage‐free ambient mass spectrometry

R Haddad, R Sparrapan… - Rapid Communications in …, 2006 - Wiley Online Library
Sonic spray ionization is shown to create a supersonic cloud of charged droplets able to
promote efficient desorption and ionization of drugs directly from the surfaces of commercial …

Development of capabilities for imaging mass spectrometry under ambient conditions with desorption electrospray ionization (DESI)

DR Ifa, JM Wiseman, Q Song, RG Cooks - International journal of mass …, 2007 - Elsevier
Aspects of the development of mass spectrometry over the past three decades are briefly
reviewed and growth points in the subject are identified. Molecular imaging by mass …

Desorption atmospheric pressure photoionization

M Haapala, J Pól, V Saarela, V Arvola… - Analytical …, 2007 - ACS Publications
An ambient ionization technique for mass spectrometry, desorption atmospheric pressure
photoionization (DAPPI), is presented, and its application to the rapid analysis of …

High-performance liquid chromatography–tandem mass spectrometry in the identification and determination of phase I and phase II drug metabolites

M Holčapek, L Kolářová, M Nobilis - Analytical and bioanalytical chemistry, 2008 - Springer
Applications of tandem mass spectrometry (MS/MS) techniques coupled with high-
performance liquid chromatography (HPLC) in the identification and determination of phase …

Simulated splashes: Elucidating the mechanism of desorption electrospray ionization mass spectrometry

AB Costa, RG Cooks - Chemical Physics Letters, 2008 - Elsevier
Recent advances in the field of ambient ionization mass spectrometry are presented briefly,
with emphasis on the technique of desorption electrospray ionization (DESI). Numerical …

What is the role of current mass spectrometry in pharmaceutical analysis?

M Khalikova, J Jireš, O Horáček… - Mass Spectrometry …, 2024 - Wiley Online Library
The role of mass spectrometry (MS) has become more important in most application
domains in recent years. Pharmaceutical analysis is specific due to its stringent regulation …

Forensic applications of desorption electrospray ionisation mass spectrometry (DESI-MS)

M Morelato, A Beavis, P Kirkbride, C Roux - Forensic science international, 2013 - Elsevier
Desorption electrospray ionisation mass spectrometry (DESI-MS) is an emerging analytical
technique that enables in situ mass spectrometric analysis of specimens under ambient …