ROS-triggered endothelial cell death mechanisms: Focus on pyroptosis, parthanatos, and ferroptosis
D Zheng, J Liu, H Piao, Z Zhu, R Wei, K Liu - Frontiers in immunology, 2022 - frontiersin.org
The endothelium is a single layer of epithelium covering the surface of the vascular system,
and it represents a physical barrier between the blood and vessel wall that plays an …
and it represents a physical barrier between the blood and vessel wall that plays an …
[HTML][HTML] Rationale for the use of N‐acetylcysteine in both prevention and adjuvant therapy of COVID‐19
S De Flora, R Balansky, S La Maestra - The FASEB journal, 2020 - ncbi.nlm.nih.gov
COVID‐19 may cause pneumonia, acute respiratory distress syndrome, cardiovascular
alterations, and multiple organ failure, which have been ascribed to a cytokine storm, a …
alterations, and multiple organ failure, which have been ascribed to a cytokine storm, a …
New insights into the role of mitochondria in cardiac microvascular ischemia/reperfusion injury
As reperfusion therapies have become more widely used in acute myocardial infarction
patients, ischemia-induced myocardial damage has been markedly reduced, but reperfusion …
patients, ischemia-induced myocardial damage has been markedly reduced, but reperfusion …
Mitochondrial glutathione: recent insights and role in disease
M Marí, E de Gregorio, C de Dios, V Roca-Agujetas… - Antioxidants, 2020 - mdpi.com
Mitochondria are the main source of reactive oxygen species (ROS), most of them deriving
from the mitochondrial respiratory chain. Among the numerous enzymatic and non …
from the mitochondrial respiratory chain. Among the numerous enzymatic and non …
Sex-specific neurotoxic effects of heavy metal pollutants: Epidemiological, experimental evidence and candidate mechanisms
The heavy metals lead (Pb), mercury (Hg), and cadmium (Cd) are ubiquitous environmental
pollutants and are known to exert severe adverse impacts on the nervous system even at …
pollutants and are known to exert severe adverse impacts on the nervous system even at …
[HTML][HTML] Sex differences in markers of oxidation and inflammation. Implications for ageing
IM de Toda, M González-Sánchez… - Mechanisms of ageing …, 2023 - Elsevier
Sexual dimorphism is a key factor to consider in the ageing process given the impact that it
has on life expectancy. The oxidative-inflammatory theory of ageing states that the ageing …
has on life expectancy. The oxidative-inflammatory theory of ageing states that the ageing …
Alterations in glutathione redox homeostasis among adolescents with obesity and anemia
D Alkazemi, A Rahman, B Habra - Scientific reports, 2021 - nature.com
Abstract The reduced (GSH)-to-oxidized (GSSG) glutathione ratio represents a dynamic
balance between oxidants and antioxidants. However, redox status in adolescents with …
balance between oxidants and antioxidants. However, redox status in adolescents with …
Oxidative stress as a common key event in developmental neurotoxicity
Y Nishimura, Y Kanda, H Sone… - Oxidative medicine and …, 2021 - Wiley Online Library
The developing brain is extremely sensitive to many chemicals. Perinatal exposure to
neurotoxicants has been implicated in several neurodevelopmental disorders, including …
neurotoxicants has been implicated in several neurodevelopmental disorders, including …
Fluorescent sensing of glutathione and related bio-applications
X Sun, F Guo, Q Ye, J Zhou, J Han, R Guo - Biosensors, 2022 - mdpi.com
Glutathione (GSH), as the most abundant low-molecular-weight biological thiol, plays
significant roles in vivo. Abnormal GSH levels have been demonstrated to be related to the …
significant roles in vivo. Abnormal GSH levels have been demonstrated to be related to the …
[HTML][HTML] The age-dependent decline of the extracellular thiol-disulfide balance and its role in SARS-CoV-2 infection
Abstract SARS–CoV-2 (COVID-19) infection can cause a severe respiratory distress
syndrome. The risk of severe manifestations and mortality characteristically increase in the …
syndrome. The risk of severe manifestations and mortality characteristically increase in the …