Diagnosis of neonatal sepsis: the past, present and future

IH Celik, M Hanna, FE Canpolat, M Pammi - Pediatric research, 2022 - nature.com
Sepsis remains a significant cause of neonatal mortality and morbidity, especially in low-and
middle-income countries. Neonatal sepsis presents with nonspecific signs and symptoms …

[HTML][HTML] Biomarkers for acute respiratory distress syndrome and prospects for personalised medicine

S Spadaro, M Park, C Turrini, T Tunstall… - Journal of …, 2019 - Springer
Acute lung injury (ALI) affects over 10% of patients hospitalised in critical care, with acute
respiratory distress syndrome (ARDS) being the most severe form of ALI and having a …

[HTML][HTML] Diagnostics for neonatal sepsis: current approaches and future directions

PY Iroh Tam, CM Bendel - Pediatric research, 2017 - nature.com
Progress has been made in the reduction of morbidity and mortality from neonatal sepsis.
However, diagnosis continues to rely primarily on conventional microbiologic techniques …

[HTML][HTML] Biomarkers of inflammation, immunosuppression and stress are revealed by metabolomic profiling of tuberculosis patients

J Weiner 3rd, SK Parida, J Maertzdorf, GF Black… - PloS one, 2012 - journals.plos.org
Although tuberculosis (TB) causes more deaths than any other pathogen, most infected
individuals harbor the pathogen without signs of disease. We explored the metabolome of> …

Urine metabolite analysis offers potential early diagnosis of ovarian and breast cancers

CM Slupsky, H Steed, TH Wells, K Dabbs… - Clinical cancer …, 2010 - AACR
Purpose: Metabolomics is a new, rapidly expanding field dedicated to the global study of
metabolites in biological systems. In this article metabolomics is applied to find urinary …

The emerging field of quantitative blood metabolomics for biomarker discovery in critical illnesses

NJ Serkova, TJ Standiford… - American journal of …, 2011 - atsjournals.org
Metabolomics, a science of systems biology, is the global assessment of endogenous
metabolites within a biologic system and represents a “snapshot” reading of gene function …

[HTML][HTML] Metabolomics and its application to acute lung diseases

KA Stringer, RT McKay, A Karnovsky… - Frontiers in …, 2016 - frontiersin.org
Metabolomics is a rapidly expanding field of systems biology that is gaining significant
attention in many areas of biomedical research. Also known as metabonomics, it comprises …

[PDF][PDF] Diagnosis of pneumococcal pneumonia: current pitfalls and the way forward

JY Song, BW Eun, MH Nahm - Infection & chemotherapy, 2013 - synapse.koreamed.org
Streptococcus pneumoniae is the most common cause of community-acquired pneumonia.
However, it can also asymptomatically colonize the upper respiratory tract. Because of the …

[HTML][HTML] A high-performing plasma metabolite panel for early-stage lung cancer detection

L Zhang, J Zheng, R Ahmed, G Huang, J Reid… - Cancers, 2020 - mdpi.com
The objective of this research is to use metabolomic techniques to discover and validate
plasma metabolite biomarkers for the diagnosis of early-stage non-small cell lung cancer …

NMR-based metabolomics strategies: plants, animals and humans

JGM Pontes, AJM Brasil, GCF Cruz, RN de Souza… - Analytical …, 2017 - pubs.rsc.org
Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful analytical platform
employed to address a diversity of issues of research such as in understanding chemical …