Gene variants and serum levels of synaptic vesicle and presynaptic plasma membrane proteins in alcohol dependence and their relationship with impulsivity and …

G Şenormancı, Ç Turan, SK Çelik, A Çelik… - Archives of Clinical …, 2021 - SciELO Brasil
Background: Exocytosis-related gene variants have been suggested to be associated with
externalizing behaviors. Objective: This study aimed to examine VAMP2 26 bp Ins\Del …

Rat model of attention-deficit hyperactivity disorder exhibits delayed recovery from acute incisional pain due to impaired descending noradrenergic inhibition

T Suto, D Kato, I Koibuchi, Y Arai, J Ohta, T Hiroki… - Scientific Reports, 2023 - nature.com
Chronic pain and attention-deficit hyperactivity disorder (ADHD) frequently coexist.
However, the common pathology is still unclear. Attenuated noradrenergic endogenous …

[HTML][HTML] Reduced fronto-striatal volume in attention-deficit/hyperactivity disorder in two cohorts across the lifespan

RB Cupertino, S Soheili-Nezhad, EH Grevet… - NeuroImage: Clinical, 2020 - Elsevier
Abstract Attention-Deficit/Hyperactivity Disorder (ADHD) has been associated with altered
brain anatomy in neuroimaging studies. However, small and heterogeneous study samples …

Exocytosis-related genes and response to methylphenidate treatment in adults with ADHD

BS Da Silva, RB Cupertino, DL Rovaris… - Molecular …, 2018 - nature.com
Experimental studies have demonstrated that methylphenidate (MPH) modulates the
synaptic vesicle trafficking and synaptotagmin-1 (SytI) mRNA levels. SytI is a regulatory …

SNARE complex polymorphisms associate with alterations of visual selective attention in Alzheimer's Disease

AS Costa, FR Guerini, B Arosio… - Journal of …, 2019 - content.iospress.com
The SNARE complex plays a crucial role in the synaptic exocytosis of neurotransmitters, a
process involved in the Alzheimer's disease (AD), the most common form of dementia. SNAP …

[HTML][HTML] The association between SYT1-rs2251214 and cocaine use disorder further supports its role in psychiatry

BS da Silva, RB Cupertino, JB Schuch… - Progress in Neuro …, 2019 - Elsevier
Synaptotagmin-1 is an essential regulator of synaptic vesicle exocytosis, and its encoding
gene (SYT1) is a genome and transcriptome-wide association hit in cognitive performance …

Paternal exposure to methylphenidate induces ADHD-like behavioral phenotypes and altered gene expressions in mouse offspring

R Nakano, A Kaizaki-Mitsumoto… - Fundamental …, 2023 - jstage.jst.go.jp
Methylphenidate (MPH) is used as a first-line treatment for attention-deficit/hyperactivity
disorder (ADHD). Because the onset of ADHD appears in early childhood and the incidence …

[PDF][PDF] Takashi Suto 1Ε, Daiki Kato, Ikuya Koibuchi, Yuki Arai, Jo Ohta, Tadanao Hiroki

H Obata, S Saito - Scientific Reports, 2023 - researchmap.jp
Results Validation of ADHD‑like behaviors of SHR. To validate SHR/Izm as an animal model
of ADHD, openfield test was performed to evaluate the locomotor activity and anxiety. SHR …

The role of SCAMP5 in central nervous system diseases

Y Chen, J Fan, D Xiao, X Li - Neurological Research, 2022 - Taylor & Francis
Objective Secretory carrier membrane proteins (SCAMPs) constitute a group of membrane
transport proteins in plants, insects and mammals. The mammalian genome contains five …

Sleep and violence perpetration: A review of biological and environmental substrates

T Paiva, H Canas‐Simião - Journal of sleep research, 2022 - Wiley Online Library
Violence is a worldwide societal burden that negatively impacts individual health, wellbeing
and economic development. Evidence suggests a bidirectional relationship between sleep …