Albumin is the most abundant circulating protein in plasma and has recently emerged as a
versatile protein carrier for drug targeting and for improving the pharmacokinetic profile of …

The field of 18F chemistry is rapidly expanding because of the use of this radionuclide in
radiotracers for positron emission tomography (PET). Until recently, most [18F]-radiotracers …

The Wacker and Wacker-type reactions are some of the most fundamental and powerful
transformations in organic chemistry for their ability to efficiently produce valuable …

Fluorine in Life Sciences: Pharmaceuticals, Medicinal Diagnostics and Agrochemicals,
volume four in Alain Tressaud's Progress in Fluorine Science series, presents a critical …

Herein we present a general protocol for the functionalization of biomolecules with an
organotrifluoroborate moiety so that they can be radiolabeled with aqueous 18F fluoride …

Unorthodox 18F-labeling strategies not employing the formation of a carbon-18F bond are
seldom found in radiochemistry. Historically, the formation of a boron-or silicon-18F bond …

Conspectus Positron emission tomography (PET) is revolutionizing our ability to visualize in
vivo targets for target validation and personalized medicine. Of several classes of imaging …

Kinins, bradykinin and kallidin are vasoactive peptides that signal through the bradykinin B1
and B2 receptors (B1R and B2R). B2R is constitutively expressed in healthy tissues and …

Melanocortin 1 receptor (MC1R) is specifically expressed in the majority of melanomas, a
leading cause of death related to skin cancers. Accurate staging and early detection is …

Radiolabelled (bio) molecules have advanced many areas of science from fundamental
biology to human health including applications in molecular imaging and more generally …