Acetoin, a high-value-added bio-based platform chemical, is widely used in foods,
cosmetics, agriculture, and the chemical industry. It is an important precursor for the …

Metabolic engineering is a powerful tool for the sustainable production of chemicals. Over
the years, the exploration of microbial, animal and plant metabolism has generated a wealth …

Given the high costs and stoichiometric amounts of reduced nicotinamide adenine
dinucleotide (NADH) required by the many oxidoreductases used for organic synthesis and …

Background To develop pathways for advanced biofuel production, and to understand the
impact of host metabolism and environmental conditions on heterologous pathway …

The production of biofuels by recombinant Escherichia coli is restricted by the toxicity of the
products. 2, 3-Butanediol (2, 3-BD), a platform and fuel bio-chemical with low toxicity to …

Biotechnological production of biofuels is restricted by toxicity of the products such as
ethanol and butanol. As its low toxicity to microbes, 2, 3-butanediol (2, 3-BD), a fuel and …

Abstract Background 2, 3-Butanediol (2, 3-BD) can be used as a liquid fuel additive to
replace petroleum oil, and as an important platform chemical in the pharmaceutical and …

Nature's two redox cofactors, nicotinamide adenine dinucleotide (NAD+) and nicotinamide
adenine dinucleotide phosphate (NADP+), are held at different reduction potentials, driving …

Diols are compounds with two hydroxyl groups and have a wide range of appealing
applications as chemicals and fuels. In particular, five low molecular diol compounds …

Cofactor engineering was employed to enhance production of acetoin by Serratia
marcescens H32. 2, 3-Butanediol was a major byproduct of acetoin fermentation by S …