New horizons for precision medicine in biliary tract cancers
JW Valle, A Lamarca, L Goyal, J Barriuso, AX Zhu - Cancer discovery, 2017 - AACR
Biliary tract cancers (BTC), including cholangiocarcinoma and gallbladder cancer, are poor-
prognosis and low-incidence cancers, although the incidence of intrahepatic …
prognosis and low-incidence cancers, although the incidence of intrahepatic …
Current and emerging therapies for advanced biliary tract cancers
Biliary tract cancers (cholangiocarcinomas and gallbladder cancers) are increasing in
incidence and have a poor prognosis. Most patients present with advanced disease, for …
incidence and have a poor prognosis. Most patients present with advanced disease, for …
Overview of current targeted therapy in gallbladder cancer
X Song, Y Hu, Y Li, R Shao, F Liu, Y Liu - Signal Transduction and …, 2020 - nature.com
Gallbladder cancer (GBC) is rare, but is the most malignant type of biliary tract tumor.
Unfortunately, only a small population of cancer patients is acceptable for the surgical …
Unfortunately, only a small population of cancer patients is acceptable for the surgical …
Integrative molecular analysis of intrahepatic cholangiocarcinoma reveals 2 classes that have different outcomes
BACKGROUND & AIMS: Cholangiocarcinoma, the second most common liver cancer, can
be classified as intrahepatic cholangiocarcinoma (ICC) or extrahepatic cholangiocarcinoma …
be classified as intrahepatic cholangiocarcinoma (ICC) or extrahepatic cholangiocarcinoma …
Pathogenesis of cholangiocarcinoma
PM Rodrigues, P Olaizola, NA Paiva… - Annual Review of …, 2021 - annualreviews.org
Cholangiocarcinoma (CCA) encompasses a group of malignancies that can arise at any
point in the biliary tree. Although considered a rare cancer, the incidence of CCA is …
point in the biliary tree. Although considered a rare cancer, the incidence of CCA is …
Evaluation and management of intrahepatic and extrahepatic cholangiocarcinoma
NF Esnaola, JE Meyer, A Karachristos, JL Maranki… - Cancer, 2016 - Wiley Online Library
Cholangiocarcinomas are rare biliary tract tumors that are often challenging to diagnose and
treat. Cholangiocarcinomas are generally categorized as intrahepatic or extrahepatic …
treat. Cholangiocarcinomas are generally categorized as intrahepatic or extrahepatic …
Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors
JB Andersen, B Spee, BR Blechacz, I Avital, M Komuta… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: Cholangiocarcinoma is a heterogeneous disease with a poor
outcome that accounts for 5%− 10% of primary liver cancers. We characterized its genomic …
outcome that accounts for 5%− 10% of primary liver cancers. We characterized its genomic …
Cediranib or placebo in combination with cisplatin and gemcitabine chemotherapy for patients with advanced biliary tract cancer (ABC-03): a randomised phase 2 trial
JW Valle, H Wasan, A Lopes, AC Backen… - The Lancet …, 2015 - thelancet.com
Background Cisplatin and gemcitabine is the standard first-line chemotherapy regimen for
patients with advanced biliary tract cancer; expression of VEGF and its receptors is …
patients with advanced biliary tract cancer; expression of VEGF and its receptors is …
Biliary tract cancer: epidemiology, radiotherapy, and molecular profiling
JA Bridgewater, KA Goodman, A Kalyan… - American Society of …, 2016 - ascopubs.org
Biliary tract cancer, or cholangiocarcinoma, arises from the biliary epithelium of the small
ducts in the periphery of the liver (intrahepatic) and the main ducts of the hilum …
ducts in the periphery of the liver (intrahepatic) and the main ducts of the hilum …
[PDF][PDF] Lusutrombopag for the treatment of thrombocytopenia in patients with chronic liver disease undergoing invasive procedures (L‐PLUS 2)
M Peck‐Radosavljevic, K Simon, A Iacobellis… - …, 2019 - Wiley Online Library
Thrombocytopenia may be associated with increased bleeding risk impacting timing and
outcome of invasive procedures in patients with chronic liver disease (CLD) …
outcome of invasive procedures in patients with chronic liver disease (CLD) …