[HTML][HTML] SARS-CoV-2 viral load and shedding kinetics

O Puhach, B Meyer, I Eckerle - Nature Reviews Microbiology, 2023 - nature.com
SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two
key parameters for estimating infectiousness. As shedding of infectious virus is required for …

SARS-CoV-2 pathogenesis

MM Lamers, BL Haagmans - Nature reviews microbiology, 2022 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
caused a devastating pandemic. Although most people infected with SARS-CoV-2 develop …

[HTML][HTML] Infectious viral load in unvaccinated and vaccinated individuals infected with ancestral, Delta or Omicron SARS-CoV-2

O Puhach, K Adea, N Hulo, P Sattonnet, C Genecand… - Nature medicine, 2022 - nature.com
Infectious viral load (VL) expelled as droplets and aerosols by infected individuals partly
determines transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Community transmission and viral load kinetics of the SARS-CoV-2 delta (B. 1.617. 2) variant in vaccinated and unvaccinated individuals in the UK: a prospective …

A Singanayagam, S Hakki, J Dunning… - The lancet infectious …, 2022 - thelancet.com
Summary Background The SARS-CoV-2 delta (B. 1.617. 2) variant is highly transmissible
and spreading globally, including in populations with high vaccination rates. We aimed to …

Visualizing in deceased COVID-19 patients how SARS-CoV-2 attacks the respiratory and olfactory mucosae but spares the olfactory bulb

M Khan, SJ Yoo, M Clijsters, W Backaert, A Vanstapel… - Cell, 2021 - cell.com
Anosmia, the loss of smell, is a common and often the sole symptom of COVID-19. The onset
of the sequence of pathobiological events leading to olfactory dysfunction remains obscure …

Rapid diagnostic testing for SARS-CoV-2

PK Drain - New England journal of medicine, 2022 - Mass Medical Soc
Key Clinical Points Rapid Diagnostic Testing for SARS-CoV-2 Rapid diagnostic tests (RDTs)
that are authorized by the Food and Drug Administration to diagnose severe acute …

Daily longitudinal sampling of SARS-CoV-2 infection reveals substantial heterogeneity in infectiousness

R Ke, PP Martinez, RL Smith, LL Gibson, A Mirza… - Nature …, 2022 - nature.com
The dynamics of SARS-CoV-2 replication and shedding in humans remain poorly
understood. We captured the dynamics of infectious virus and viral RNA shedding during …

Immunology of SARS-CoV-2 infection in children

J Chou, PG Thomas, AG Randolph - Nature immunology, 2022 - nature.com
Children and adolescents exhibit a broad range of clinical outcomes from SARS-CoV-2
infection, with the majority having minimal to mild symptoms. Additionally, some succumb to …

An upper bound on one-to-one exposure to infectious human respiratory particles

G Bagheri, B Thiede, B Hejazi… - Proceedings of the …, 2021 - National Acad Sciences
There is ample evidence that masking and social distancing are effective in reducing severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. However, due to the …

Spatiotemporal invasion dynamics of SARS-CoV-2 lineage B. 1.1. 7 emergence

MUG Kraemer, V Hill, C Ruis, S Dellicour, S Bajaj… - Science, 2021 - science.org
Understanding the causes and consequences of the emergence of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) variants of concern is crucial to pandemic control yet …