The role of the microbiota in periodontal disease
MA Curtis, PI Diaz, TE Van Dyke - Periodontology 2000, 2020 - Wiley Online Library
The last decade has witnessed unparalleled advances in our understanding of the
complexity of the oral microbiome and the compositional changes that occur in subgingival …
complexity of the oral microbiome and the compositional changes that occur in subgingival …
Current understanding of periodontal disease pathogenesis and targets for host‐modulation therapy
G Hajishengallis, T Chavakis… - Periodontology 2000, 2020 - Wiley Online Library
Recent advances indicate that periodontitis is driven by reciprocally reinforced interactions
between a dysbiotic microbiome and dysregulated inflammation. Inflammation is not only a …
between a dysbiotic microbiome and dysregulated inflammation. Inflammation is not only a …
Current concepts in the pathogenesis of periodontitis: from symbiosis to dysbiosis
AA Abdulkareem, FB Al-Taweel… - Journal of Oral …, 2023 - Taylor & Francis
The primary etiological agent for the initiation and progression of periodontal disease is the
dental plaque biofilm which is an organized aggregation of microorganisms residing within a …
dental plaque biofilm which is an organized aggregation of microorganisms residing within a …
The oral microbiota: dynamic communities and host interactions
RJ Lamont, H Koo, G Hajishengallis - Nature reviews microbiology, 2018 - nature.com
The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as
dental caries and periodontitis, two of the most prevalent microbially induced disorders …
dental caries and periodontitis, two of the most prevalent microbially induced disorders …
Polarized macrophages in periodontitis: characteristics, function, and molecular signaling
X Sun, J Gao, X Meng, X Lu, L Zhang… - Frontiers in …, 2021 - frontiersin.org
Periodontitis (PD) is a common chronic infectious disease. The local inflammatory response
in the host may cause the destruction of supporting periodontal tissue. Macrophages play a …
in the host may cause the destruction of supporting periodontal tissue. Macrophages play a …
Polymicrobial communities in periodontal disease: Their quasi‐organismal nature and dialogue with the host
G Hajishengallis, RJ Lamont - Periodontology 2000, 2021 - Wiley Online Library
In health, indigenous polymicrobial communities at mucosal surfaces maintain an ecological
balance via both inter‐microbial and host‐microbial interactions that promote their own and …
balance via both inter‐microbial and host‐microbial interactions that promote their own and …
The role of micronutrients in support of the immune response against viral infections
F Pecora, F Persico, A Argentiero, C Neglia, S Esposito - Nutrients, 2020 - mdpi.com
Viral infections are a leading cause of morbidity and mortality worldwide, and the importance
of public health practices including handwashing and vaccinations in reducing their spread …
of public health practices including handwashing and vaccinations in reducing their spread …
The role of inflammation and genetics in periodontal disease
BG Loos, TE Van Dyke - Periodontology 2000, 2020 - Wiley Online Library
Periodontitis is a complex disease:(a) various causative factors play a role simultaneously
and interact with each other; and (b) the disease is episodic in nature, and bursts of disease …
and interact with each other; and (b) the disease is episodic in nature, and bursts of disease …
Mimicking biofilm formation and development: Recent progress in in vitro and in vivo biofilm models
I Guzmán-Soto, C McTiernan, M Gonzalez-Gomez… - Iscience, 2021 - cell.com
Biofilm formation in living organisms is associated to tissue and implant infections, and it has
also been linked to the contribution of antibiotic resistance. Thus, understanding biofilm …
also been linked to the contribution of antibiotic resistance. Thus, understanding biofilm …
The nexus between periodontal inflammation and dysbiosis
TE Van Dyke, PM Bartold, EC Reynolds - Frontiers in immunology, 2020 - frontiersin.org
The nexus between periodontal inflammation and the polymicrobial biofilm in the gingival
sulcus is critical to understanding the pathobiology of periodontitis. Both play a major role in …
sulcus is critical to understanding the pathobiology of periodontitis. Both play a major role in …