[PDF][PDF] A brief review on importance of DFT in drug design

H Tandon, T Chakraborty, V Suhag - Res. Med. Eng. Sci, 2019 - researchgate.net
Abstract Density Functional Theory (DFT) is progressively becoming vital for the drug
designing process. Since past few years DFT has appeared as a Quantum Mechanical (QM) …

Mechanism of Brønsted acid-catalyzed conversion of carbohydrates

G Yang, EA Pidko, EJM Hensen - Journal of catalysis, 2012 - Elsevier
A comprehensive DFT study of acid-catalyzed glucose and fructose reactions in water
covering more than 100 potential reaction paths is performed with the aim to identify the …

Microwave spectroscopy of biomolecular building blocks

JL Alonso, JC López - Gas-Phase IR Spectroscopy and Structure of …, 2015 - Springer
Microwave spectroscopy, considered as the most definitive gas phase structural probe, is
able to distinguish between different conformational structures of a molecule, because they …

Mechanism and Origins of Selectivity in the Supramolecular [Ga4L6]12–-Catalyzed Aza-Prins Reaction: The Mechanistic Studies

N Li, Q Wang, S Zhuo, LP Xu - ACS Catalysis, 2023 - ACS Publications
The mechanism, reactivity, and selectivity of the aza-Prins reaction in both the bulk solution
and under [Ga4L6] 12-(L= N, N-bis (2, 3-dihydroxybenzoyl)-1, 5-diaminonaphthalene) …

The conformational behaviour of free D-glucose—at last

JL Alonso, MA Lozoya, I Pena, JC López… - Chemical …, 2014 - pubs.rsc.org
The conformational behaviour of isolated D-glucose has been revealed in this work using
Fourier transform microwave spectroscopy coupled with laser ablation of crystalline α-and β …

(α-Monofluoroalkyl) phosphonates: a class of isoacidic and “tunable” mimics of biological phosphates

DB Berkowitz, M Bose - Journal of Fluorine Chemistry, 2001 - Elsevier
In the early 1980s, Blackburn and McKenna suggested that α-fluorination might lead to
phosphonates that better mimic natural phosphates. Although α-monofluorination produces …

Toward a physical interpretation of substituent effects: the case of fluorine and trifluoromethyl groups

T Siodła, WP Oziminski, M Hoffmann… - The Journal of …, 2014 - ACS Publications
The application of ab initio and DFT computational methods at six different levels of theory
(MP2/cc-pVDZ, MP2/aug-cc-pVTZ, B3LYP/cc-pVDZ, B3LYP/aug-cc-pVTZ, M06/cc-pVDZ …

Polarizable empirical force field for hexopyranose monosaccharides based on the classical drude oscillator

DS Patel, X He, AD MacKerell Jr - The Journal of Physical …, 2015 - ACS Publications
A polarizable empirical force field based on the classical Drude oscillator is presented for
the hexopyranose form of selected monosaccharides. Parameter optimization targeted …

Weak Hydrogen Bridges: A Systematic Theoretical Study on the Nature and Strength of C H⋅⋅⋅ F C Interactions

I Hyla‐Kryspin, G Haufe… - Chemistry–A European …, 2004 - Wiley Online Library
We present a comparative study on the nature and strength of weak hydrogen bonding
between the C (sp3) H, C (sp2) H, and C (sp) H donor bonds and F C (sp3) acceptors …

Conformational properties of α-or β-(1→ 6)-linked oligosaccharides: Hamiltonian replica exchange MD simulations and NMR experiments

DS Patel, R Pendrill, SS Mallajosyula… - The Journal of …, 2014 - ACS Publications
Conformational sampling for a set of 10 α-or β-(1→ 6)-linked oligosaccharides has been
studied using explicit solvent Hamiltonian replica exchange (HREX) simulations and NMR …