The new (dis) order in RNA regulation
AI Järvelin, M Noerenberg, I Davis… - Cell Communication and …, 2016 - Springer
RNA-binding proteins play a key role in the regulation of all aspects of RNA metabolism,
from the synthesis of RNA to its decay. Protein-RNA interactions have been thought to be …
from the synthesis of RNA to its decay. Protein-RNA interactions have been thought to be …
RNA-binding proteins and their role in kidney disease
L Seufert, T Benzing, M Ignarski… - Nature Reviews …, 2022 - nature.com
RNA-binding proteins (RBPs) are of fundamental importance for post-transcriptional gene
regulation and protein synthesis. They are required for pre-mRNA processing and for RNA …
regulation and protein synthesis. They are required for pre-mRNA processing and for RNA …
Signatures within the esophageal microbiome are associated with host genetics, age, and disease
NP Deshpande, SM Riordan, N Castaño-Rodríguez… - Microbiome, 2018 - Springer
Background The esophageal microbiome has been proposed to be involved in a range of
diseases including the esophageal adenocarcinoma cascade; however, little is currently …
diseases including the esophageal adenocarcinoma cascade; however, little is currently …
IL-10 is required for polarization of macrophages to M2-like phenotype by mycobacterial DnaK (heat shock protein 70)
RL Lopes, TJ Borges, RF Zanin, C Bonorino - Cytokine, 2016 - Elsevier
Macrophages are key cells in the innate immune system. They phagocytose pathogens and
cellular debris, promote inflammation, and have important roles in tumor immunity …
cellular debris, promote inflammation, and have important roles in tumor immunity …
Role of eukaryotic initiation factors during cellular stress and cancer progression
DK Sharma, K Bressler, H Patel… - Journal of nucleic …, 2016 - Wiley Online Library
Protein synthesis can be segmented into distinct phases comprising mRNA translation
initiation, elongation, and termination. Translation initiation is a highly regulated and rate …
initiation, elongation, and termination. Translation initiation is a highly regulated and rate …
Ion channel dysfunction in cerebellar ataxia
DD Bushart, VG Shakkottai - Neuroscience letters, 2019 - Elsevier
Cerebellar ataxias constitute a heterogeneous group of disorders that result in impaired
speech, uncoordinated limb movements, and impaired balance, often ultimately resulting in …
speech, uncoordinated limb movements, and impaired balance, often ultimately resulting in …
[HTML][HTML] The combination of piR-823 and eukaryotic initiation factor 3 B (EIF3B) activates hepatic stellate cells via upregulating TGF-β1 in liver fibrogenesis
X Tang, X Xie, X Wang, Y Wang, X Jiang… - … medical journal of …, 2018 - ncbi.nlm.nih.gov
Background Piwi-interacting RNA (piRNA) is the largest class of small non-coding RNA,
which has also been identified in somatic tissues, and aberrant expression of piRNAs in …
which has also been identified in somatic tissues, and aberrant expression of piRNAs in …
P311 promotes renal fibrosis via TGFβ1/Smad signaling
Z Yao, S Yang, W He, L Li, R Xu, X Zhang, H Li… - Scientific reports, 2015 - nature.com
P311, a gene that was identified in 1993, has been found to have diverse biological
functions in processes such as cell proliferation, migration and differentiation. However, its …
functions in processes such as cell proliferation, migration and differentiation. However, its …
[HTML][HTML] The silencing of NREP aggravates OA cartilage damage through the TGF-β1/Smad2/3 pathway in chondrocytes
Y Liu, M Liu, C Zhang, X Li, S Zheng, L Wen… - Journal of Orthopaedic …, 2024 - Elsevier
Background Osteoarthritis (OA) is a common chronic degenerative joint disease. Due to the
limited understanding of its complex pathological mechanism, there is currently no effective …
limited understanding of its complex pathological mechanism, there is currently no effective …
Overexpression of NREP promotes migration and invasion in gastric cancer through facilitating epithelial-mesenchymal transition
Y Liu, S Zeng, Y Hu, Y Zhang, J Li - Frontiers in Cell and …, 2021 - frontiersin.org
The identification of biomarkers and effective therapeutic targets for gastric cancer (GC), the
most common cause of cancer-related deaths around the world, is currently a major focus …
most common cause of cancer-related deaths around the world, is currently a major focus …