Targeting RAGE-signaling pathways in the repair of rotator-cuff injury

V Rai, V Deepu, DK Agrawal - Molecular and Cellular Biochemistry, 2024 - Springer
Rotator cuff injury (RCI) is a common musculoskeletal problem that can have a significant
impact on the quality of life and functional abilities of those affected. Novel therapies …

[HTML][HTML] Understanding Fibrous Tissue in the Effective Healing of Rotator Cuff Injury

R Rajalekshmi, DK Agrawal - Journal of surgery and research, 2024 - ncbi.nlm.nih.gov
The rotator cuff is a crucial group of muscles and tendons in the shoulder complex that plays
a significant role in the stabilization of the glenohumeral joint and enabling a wide range of …

[HTML][HTML] Mitochondrial Biogenesis as a Therapeutic Target for Rotator Cuff Tendon Tears

AN Yazdani, A Abdi, P Patel, P Velpuri… - … of orthopaedics and …, 2023 - ncbi.nlm.nih.gov
Abstract Rotator Cuff Injuries (RCI) are highly prevalent and characterized by shoulder pain,
restricted shoulder movement, and difficulty with overhead activity, radiating pain in the …

Chronic Adaptation of Achilles Tendon Tissues upon Injury to Rotator Cuff Tendon in Hyperlipidemic Swine

MR Lal, DK Agrawal - Journal of orthopaedics and sports …, 2024 - pmc.ncbi.nlm.nih.gov
The biomechanical properties of the tendon are affected due to the changes in composition
of the tendon extracellular matrix (ECM). Age, overuse, trauma and metabolic disorders are …

[HTML][HTML] Biologically enhanced patch in the healing and mechanical stability of rotator cuff tears

MRL Lp, DK Agrawal - Journal of biotechnology and …, 2024 - pmc.ncbi.nlm.nih.gov
Biological patches have emerged as promising adjuncts in the surgical management of
rotator cuff tears, aiming to enhance tissue healing and biomechanical properties of repaired …

[HTML][HTML] Hyperlipidemia Induced Pathological Changes with no Effect in Biomechanical Properties in the Achilles Tendon of Young Swine

MRL LP, DK Agrawal - Journal of orthopaedics and sports …, 2024 - ncbi.nlm.nih.gov
Hyperlipidemia is linked to atherosclerosis and various diseases. Its strong association with
Achilles tendinopathies and xanthomas affects tendon properties through lipid deposition in …

[HTML][HTML] Rotator Cuff Injury: Pathogenesis, Biomechanics, and Repair

P Sripathi, DK Agrawal - Journal of orthopaedics and sports …, 2024 - pmc.ncbi.nlm.nih.gov
Anterior Rotator cuff tears are one of the most common surgically addressed disorders, as
the tears in the tendon can affect anyone regardless of risk factors or activity level. The …

14-3-3ζ: An Optimal Housekeeping Protein for Western Blot Analysis in Swine Rotator Cuff Tendon Studies

R Rajalekshmi, V Rai, DK Agrawal - 2024 - researchsquare.com
Healthy biomechanics of the shoulder involving rotator cuff muscles and rotator cuff tendon
(RCT) is pivotal for joint stability, yet co-morbid conditions like hyperlipidemia and …