Transposable elements in normal and malignant hematopoiesis
E Lemerle, E Trompouki - Disease Models & Mechanisms, 2023 - journals.biologists.com
Transposable elements (TEs) are dispersed repetitive DNA sequences that can move within
a genome. Even though hundreds of years of evolution have led to the accumulation of …
a genome. Even though hundreds of years of evolution have led to the accumulation of …
From the genome's perspective: Bearing somatic retrotransposition to leverage the regulatory potential of L1 RNAs
D Mangoni, A Mazzetti, F Ansaloni, A Simi… - …, 2024 - Wiley Online Library
Transposable elements (TEs) are mobile genomic elements constituting a big fraction of
eukaryotic genomes. They ignite an evolutionary arms race with host genomes, which in turn …
eukaryotic genomes. They ignite an evolutionary arms race with host genomes, which in turn …
LINE-1 mRNA 3′ end dynamics shape its biology and retrotransposition potential
Abstract LINE-1 (L1) retrotransposons are mobile genetic elements that create new genomic
insertions by a copy-paste mechanism involving L1 RNA/RNP intermediates. L1 encodes …
insertions by a copy-paste mechanism involving L1 RNA/RNP intermediates. L1 encodes …
Retrotransposon life cycle and its impacts on cellular responses
A Luqman-Fatah, K Nishimori, S Amano, Y Fumoto… - RNA biology, 2024 - Taylor & Francis
Approximately 45% of the human genome is comprised of transposable elements (TEs),
also known as mobile genetic elements. However, their biological function remains largely …
also known as mobile genetic elements. However, their biological function remains largely …
Every repeat is unique: Exploring the genomic impact of human L1 retrotransposons at locus-specific resolution
S Workman, SR Richardson - Cell Genomics, 2024 - cell.com
Fully understanding the impact of the human retrotransposon L1 requires that each of∼
500,000 L1 copies be evaluated as a potentially unique genomic entity. In this issue of Cell …
500,000 L1 copies be evaluated as a potentially unique genomic entity. In this issue of Cell …
The discovery of multiple active mys-related LTR-retroelements within the Neotominae subfamily of cricetid rodents
DH Kass, S Beatty, A Smith, M Scott, D Shah… - Genetica, 2023 - Springer
Retrotransposon families in the rodent family Cricetidae have been understudied in contrast
to Muridae, both taxa classified within the superfamily Muroidea. Therefore, we carried out a …
to Muridae, both taxa classified within the superfamily Muroidea. Therefore, we carried out a …
[PDF][PDF] ANÁLISIS DEL RETROTRANSPOSON LINE-1 COMO MARCADOR DE SENESCENCIA EN EL MODELO MURINO DE ENVEJECIMIENTO ACELERADO …
TV HERRERA - 2023 - ru.dgb.unam.mx
La senescencia celular es un estado celular caracterizado por un arresto irreversible del
ciclo celular, y puede ser desencadenada por daño en el DNA, acortamiento de los …
ciclo celular, y puede ser desencadenada por daño en el DNA, acortamiento de los …
[PDF][PDF] The interferon-stimulated gene product HELZ2 destabilizes human LINE-1 RNA to inhibit LINE-1 retrotransposition and the associated type I interferon …
A Luqman Bin Abdul Fatah - 2023 - repository.kulib.kyoto-u.ac.jp
Interferon-stimulated genes (ISGs) are upregulated in response to pathogen infection as a
defense mechanism; several ISG-encoded proteins were previously reported to inhibit …
defense mechanism; several ISG-encoded proteins were previously reported to inhibit …