Regulated cell death is intrinsically associated with inflammatory liver disease and is pivotal
in governing outcomes of metabolic liver disease. Different types of cell death may coexist …

Necroptosis is a regulated caspase-independent form of necrotic cell death that results in an
inflammatory phenotype. This process contributes profoundly to the pathophysiology of …

Necroptosis is a lytic, inflammatory form of cell death that not only contributes to pathogen
clearance but can also lead to disease pathogenesis. Necroptosis is triggered by RIPK3 …

Immunogenic cell death (ICD) is a stress-driven form of regulated cell death (RCD) in which
dying tumor cells' specific signaling pathways are activated to release damage-associated …

Bladder cancer is a malignant tumor of the urinary system and is one of the most common
cancers worldwide. Lipoxygenases are closely related to the development of various …

Significance: Kidney diseases remain a worldwide public health problem resulting in
millions of deaths each year; they are characterized by progressive destruction of renal …

As an alternative pathway of controlled cell death, necroptosis can be triggered by tumor
necrosis factor via the kinases RIPK1/RIPK3 and the effector protein mixed-lineage kinase …

Ultraviolet radiation (UVR) is a major environmental mutagen. In skin, UVR can initiate
cancer through the induction of mutagenic DNA damage and promote its progression. An …

Metal and metal oxide nanoparticles, including copper nanoparticles (CuNPs), display
antimicrobial activities and are regarded as promising microorganism inhibitors. Here, we …

Necroptosis is a form of programmed cell death. Mixed lineage kinase domain-like protein
(MLKL) is the necroptosis executor, and it is involved in various diseases such as tissue …