Targeting and regulation of autophagy in hepatocellular carcinoma: revisiting the molecular interactions and mechanisms for new therapy approaches
M Hashemi, N Nadafzadeh, MH Imani, R Rajabi… - Cell Communication and …, 2023 - Springer
Autophagy is an evolutionarily conserved process that plays a role in regulating
homeostasis under physiological conditions. However, dysregulation of autophagy is …
homeostasis under physiological conditions. However, dysregulation of autophagy is …
HIF-1α-induced expression of m6A reader YTHDF1 drives hypoxia-induced autophagy and malignancy of hepatocellular carcinoma by promoting ATG2A and ATG14 …
Q Li, Y Ni, L Zhang, R Jiang, J Xu, H Yang… - Signal transduction and …, 2021 - nature.com
Abstract N6-methyladenosine (m6A), and its reader protein YTHDF1, play a pivotal role in
human tumorigenesis by affecting nearly every stage of RNA metabolism. Autophagy …
human tumorigenesis by affecting nearly every stage of RNA metabolism. Autophagy …
Autophagy-related microRNAs: possible regulatory roles and therapeutic potential in and gastrointestinal cancers
MH Pourhanifeh, M Vosough… - Pharmacological …, 2020 - Elsevier
Gastrointestinal (GI) cancers with a high incidence rate and adverse complications are
associated with severe morbidity and mortality around the world. It is well recognized that …
associated with severe morbidity and mortality around the world. It is well recognized that …
[HTML][HTML] lncRNA SNHG11 promotes gastric cancer progression by activating the Wnt/β-catenin pathway and oncogenic autophagy
Q Wu, J Ma, J Wei, W Meng, Y Wang, M Shi - Molecular Therapy, 2021 - cell.com
Long non-coding RNAs (lncRNAs) are under active investigation in the development of
cancers, including gastric cancer (GC). Oncogenic autophagy is required for cancer cell …
cancers, including gastric cancer (GC). Oncogenic autophagy is required for cancer cell …
Exosomal circRELL1 serves as a miR-637 sponge to modulate gastric cancer progression via regulating autophagy activation
H Sang, W Zhang, L Peng, S Wei, X Zhu, K Huang… - Cell Death & …, 2022 - nature.com
Circular RNAs (circRNAs) play a vital role in the occurrence and development of tumors,
including gastric cancer (GC). However, there are still many circRNAs related to GC whose …
including gastric cancer (GC). However, there are still many circRNAs related to GC whose …
miR‐155‐5p inhibition rejuvenates aged mesenchymal stem cells and enhances cardioprotection following infarction
Y Hong, H He, G Jiang, H Zhang, W Tao, Y Ding… - Aging cell, 2020 - Wiley Online Library
Aging impairs the functions of human mesenchymal stem cells (MSCs), thereby severely
reducing their beneficial effects on myocardial infarction (MI). MicroRNAs (miRNAs) play …
reducing their beneficial effects on myocardial infarction (MI). MicroRNAs (miRNAs) play …
Circular CPM promotes chemoresistance of gastric cancer via activating PRKAA2‐mediated autophagy
L Fang, J Lv, Z Xuan, B Li, Z Li, Z He… - Clinical and …, 2022 - Wiley Online Library
Background Chemotherapy can significantly improve the disease‐free survival and overall
survival of patients with advanced gastric cancer (GC). 5‐fluorouracil (5‐FU) is frequently …
survival of patients with advanced gastric cancer (GC). 5‐fluorouracil (5‐FU) is frequently …
[HTML][HTML] The emerging roles of autophagy-related microRNAs in cancer
C Shan, X Chen, H Cai, X Hao, J Li… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Autophagy is a conserved catabolic process involving the degradation and recycling of
damaged biomacromolecules or organelles through lysosomal-dependent pathways and …
damaged biomacromolecules or organelles through lysosomal-dependent pathways and …
MicroRNAs play an essential role in autophagy regulation in various disease phenotypes
Y Zhao, Z Wang, W Zhang, L Zhang - Biofactors, 2019 - Wiley Online Library
Autophagy is a highly conserved catabolic process and fundamental biological process in
eukaryotic cells. It recycles intracellular components to provide nutrients during starvation …
eukaryotic cells. It recycles intracellular components to provide nutrients during starvation …
miR-210-5p promotes epithelial–mesenchymal transition by inhibiting PIK3R5 thereby activating oncogenic autophagy in osteosarcoma cells
W Liu, D Jiang, F Gong, Y Huang, Y Luo, Y Rong… - Cell death & …, 2020 - nature.com
Osteosarcoma (OS) is a malignant bone tumor which occurs mainly in adolescents with
frequent pulmonary metastasis and a high mortality rate. Accumulating evidence has …
frequent pulmonary metastasis and a high mortality rate. Accumulating evidence has …